Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Finite-Element Analysis of Local Flux Density Variation Considering PWM Current Harmonics
, 2018 Large amounts of harmonics are contained in the current as the motor is driven by pulse width modulation (PWM). Significant amounts of computing time are required to compute local flux density variation considering such current harmonics.
홍정표
core +1 more source
Different LED Light Wavelengths and Photosynthetic Photon Flux Density Effect on Colletotrichum acutatum Growth. [PDF]
Plants (Basel), 2022 Rasiukevičiūtė N +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Exploration of the Magnetic Flux Density on the Surface of Seamless Knitted Fabrics Manufactured with Magnetic Polypropylene Fibers. [PDF]
Materials (Basel), 2022 Xiang Y +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Photosynthetic responses of Eulophia dentata, Bletilla formosana, and Saccharum spontaneum under various photosynthetic photon flux density conditions. [PDF]
Photosynthetica, 2022 Lai YH +6 more
europepmc +1 more source
Citation: 'particle flux density' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.08747 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Photosynthetic photon flux density affects fruit biomass radiation-use efficiency of dwarf tomatoes under LED light at the reproductive growth stage. [PDF]
Front Plant Sci, 2023 Ke X, Yoshida H, Hikosaka S, Goto E.
europepmc +1 more source