Results 241 to 250 of about 713,945 (299)

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Low-pressure storms drive nitrous oxide emissions in the Southern Ocean. [PDF]

Nat Commun
Kelly CL, Chang BX, Emmanuelli AF, Park ER, Macdonald AM, Nicholson DP.   +5 more
europepmc   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Carbon Fluxes of Contrasting Degraded Peatland Pilot Sites During Early-stage Restoration: Ex-milled Bare Peat and Grazed Grassland Conversion. [PDF]

Environ Manage
Keightley AT, Field CD, Longden M, Caporn SJM.   +3 more
europepmc   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Greenhouse gas and ammonia emissions from duckweed cultivation systems using diluted liquid manure. [PDF]

Sci Rep
Stadtlander T, Gomez DM, Müller R, Baki C, Brueggemann N, Leiber F, Krause HM, Agostini L.   +7 more
europepmc   +1 more source

An observational case study for inorganic nitrogen dry deposition potential on sea-surface primary production in the subtropical, western North Pacific. [PDF]

Sci Rep
Taketani F, Matsumoto K, Sekiya T, Yamaji K, Kanaya Y.   +4 more
europepmc   +1 more source

Predicting the role of inequalities on human mobility patterns. [PDF]

PNAS Nexus
Boldini A, De Lellis P, Imperatore S, Das R, Ceferino L, Heitor M, Porfiri M.   +6 more
europepmc   +1 more source

A multiscale theory for network advection- reaction-diffusion. [PDF]

J Math Biol
Oliveri H, Cozzolino E, Goriely A.
europepmc   +1 more source

How does thinning affect the carbon budget of a subtropical coniferous plantation? [PDF]

Carbon Balance Manag
Xu M, Li S, Yang F, Zhang T, Liu X, Zhang H, Wang Y, Song J, Wang Z, Zhu X, Cheng C, Wang J, Wang H.   +12 more
europepmc   +1 more source