Results 1 to 10 of about 928,062 (310)

[14C]-Tryptophan Metabolic Tracing in Liver Cancer Cells

Bio-Protocol, 2015
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for many NAD+-consuming proteins with diverse biological functions. Oscillations in NAD+ levels may influence several cellular signaling pathways.
Krishna Tummala, Nabil Djouder
doaj   +1 more source

Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells

Cell Reports, 2017
Summary: Hepatocellular carcinoma (HCC) is an aggressive primary liver cancer. However, its origin remains a debated question. Using human data and various hepatocarcinogenesis mouse models, we show that, in early stages, transformed hepatocytes ...
Krishna S. Tummala, Marta Brandt, Ana Teijeiro, Osvaldo Graña, Robert F. Schwabe, Cristian Perna, Nabil Djouder   +6 more
doaj   +1 more source

Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing

Cell Reports Medicine, 2020
Summary: Enteroviruses are suspected to contribute to insulin-producing β cell loss and hyperglycemia-induced diabetes. However, mechanisms are not fully defined.
Hugo Bernard, Ana Teijeiro, Almudena Chaves-Pérez, Cristian Perna, Basanthi Satish, Anna Novials, Jennifer P. Wang, Nabil Djouder   +7 more
doaj   +1 more source

Release dynamics and plant availability of POLY4 fertilizer nutrients in tropical acidic soils

Scientific Reports
POLY4 is a polyhalite-based mineral fertilizer containing essential nutrients for crop growth and development. Dissolution of POLY4 and its nutrient availability to crops in acidic tropical soils are currently deemed inadequate.
Mohamed Musa Hanafi, Dadang Gusyana, Alexey Shcherbakov, Roy Moore, Ross Mitchell   +4 more
doaj   +1 more source

Variability of drinking water for pigs and poutry the southern region of Brazil over a twelve – month period

Revista Brasileira de Engenharia de Biossistemas
The increase in global food demand has led to intensified production of pigs and poultry. In this context, water quality on farms needs to be monitored to ensure maximum production and animal welfare.
Vitória Fernanda Bayer, Ana Luísa da Costa, Michele Fangmeier, Luiza Marchiori Severo, Daiane Carvalho, Claus André Kettermann, Luana Specht, Fernanda Richter, Davi Massi, Jacir Massi, Maycon de Campos, Nathan Pitter Pieta Biavatti   +11 more
doaj   +1 more source

IL-17A produced by POMC neurons regulates diet-induced obesity

iScience
Summary: Overeating leads to obesity, a low-grade inflammatory condition involving interleukin-17A (IL-17A). While pro-opiomelanocortin (POMC) neurons regulate feeding, their connection with IL-17A is not well understood.
Rosa Gallo, Ana Teijeiro, Mariana Angulo-Aguado, Nabil Djouder   +3 more
doaj   +1 more source

The forgotten art of cold therapeutic properties in cancer: A comprehensive historical guideGlossary

iScience, 2023
Summary: Cold therapy has been used for centuries, from Julius Caesar to Mohandas Gandhi, as a potent therapeutic approach. However, it has been largely forgotten in modern medicine.
Tatiana P. Grazioso, Nabil Djouder
doaj   +1 more source

Combining Proteomics and Metabolomics to Analyze the Effects of Spaceflight on Rice Progeny

Frontiers in Plant Science, 2022
Spaceflight is a special abiotic stress, the biological effect mechanism of which on contemporary rice has been clarified, However, its effect on offspring rice was still unclear.
Deyong Zeng, Deyong Zeng, Deyong Zeng, Jie Cui, Jie Cui, Yishu Yin, Yishu Yin, Cuihong Dai, Cuihong Dai, Haitian Zhao, Haitian Zhao, Chen Song, Chen Song, Shuanghong Guan, Shuanghong Guan, Dayou Cheng, Dayou Cheng, Yeqing Sun, Weihong Lu, Weihong Lu, Weihong Lu   +20 more
doaj   +1 more source

Performance of castor in heavy metal polluted soils under the treatment of various decontaminants

Environment Conservation Journal, 2023
In order to find out the performance of castor under decontaminant treated heavy metal polluted soils, an experiment was conducted at Students Farm, College of Agriculture, PJTSAU, Rajendranagar, Hyderabad, during kharif 2016 to study the performance of
Y Balachandra, M. Chandini Patnaik, G. Padmaja, G.E.CH. Vidya Sagar, S. Biswabara   +4 more
doaj   +1 more source

Cold exposure reinstates NAD+ levels and attenuates hepatocellular carcinoma

Cell Stress
Cold exposure has been historically used for medicinal purposes, but its benefits and associated mechanisms in mammalian organisms still remain unclear.
Tatiana P Grazioso, Maria del Mar Rigual, Cristian Perna, Eduardo J Caleiras, Nabil Djouder   +4 more
doaj   +1 more source