Results 21 to 30 of about 1,576,936 (310)

Diet, Microbiota, and Colorectal Cancer

open access: yesiScience, 2019
The intestinal epithelium is a very dynamic tissue under a high regenerative pressure, which makes it susceptible to malignant transformation. Proper integration of various cell signaling pathways and a balanced cross talk between different cell types ...
Tatiana P. Grazioso   +2 more
doaj   +1 more source

Effects of Space Flight on Expression of Key Proteins in Rice Leaves

open access: yesRice Science, 2020
As a unique form of abiotic stress, the environmental conditions of outer space are expected to induce changes in plant genomes, proteomes and metabolic pathways.
Zeng Deyong   +8 more
doaj   +1 more source

Eating behaviours and food cravings; influence of age, sex, BMI and FTO genotype [PDF]

open access: yes, 2019
Previous studies indicate that eating behaviours and food cravings are associated with increased BMI and obesity. However, the interaction between these behaviours and other variables such as age, sex, BMI and genetics is complex.
Caroline Dalton   +5 more
core   +1 more source

Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing

open access: yesCell Reports Medicine, 2020
Summary: Enteroviruses are suspected to contribute to insulin-producing β cell loss and hyperglycemia-induced diabetes. However, mechanisms are not fully defined.
Hugo Bernard   +7 more
doaj   +1 more source

Toward the replacement of conventional fertilizer with polyhalite in eastern China to improve peanut growth and soil quality

open access: yesChemical and Biological Technologies in Agriculture, 2022
Background Polyhalite fertilizer application is an effective way to alleviate a shortage of potassium. This study explored the effects of polyhalite fertilizer application as a total or partial replacement for conventional potassium fertilizer to improve
Huiting Tan   +9 more
doaj   +1 more source

Real-world outcomes of managing autosomal-dominant polycystic kidney disease using a medical food as part of a nutrition and lifestyle program to improve renal and metabolic health

open access: yesFrontiers in Nutrition
BackgroundAutosomal-dominant polycystic kidney disease (ADPKD) is a common hereditary form of chronic kidney disease with limited pharmacological treatment options.
Emily Muensterman   +2 more
doaj   +1 more source

[14C]-Tryptophan Metabolic Tracing in Liver Cancer Cells

open access: yesBio-Protocol, 2015
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for many NAD+-consuming proteins with diverse biological functions. Oscillations in NAD+ levels may influence several cellular signaling pathways.
Krishna Tummala, Nabil Djouder
doaj   +1 more source

Combining Proteomics and Metabolomics to Analyze the Effects of Spaceflight on Rice Progeny

open access: yesFrontiers in Plant Science, 2022
Spaceflight is a special abiotic stress, the biological effect mechanism of which on contemporary rice has been clarified, However, its effect on offspring rice was still unclear.
Deyong Zeng   +20 more
doaj   +1 more source

Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells

open access: yesCell Reports, 2017
Summary: Hepatocellular carcinoma (HCC) is an aggressive primary liver cancer. However, its origin remains a debated question. Using human data and various hepatocarcinogenesis mouse models, we show that, in early stages, transformed hepatocytes ...
Krishna S. Tummala   +6 more
doaj   +1 more source

The forgotten art of cold therapeutic properties in cancer: A comprehensive historical guideGlossary

open access: yesiScience, 2023
Summary: Cold therapy has been used for centuries, from Julius Caesar to Mohandas Gandhi, as a potent therapeutic approach. However, it has been largely forgotten in modern medicine.
Tatiana P. Grazioso, Nabil Djouder
doaj   +1 more source

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