Results 151 to 160 of about 7,295 (180)
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Vaccine, 2001
A replication-defective adenovirus 5 encoding foot-and-mouth disease virus (FMDV) capsid and 3C proteinase coding regions (Ad5-FMDV3CWT) was used to vaccinate swine. A single inoculation utilizing 1 x 10(8) plaque forming units (pfu) or an inoculation of 1 x 10(8) followed by a boost of 5 x 10(8) pfu Ad5-FMDV3CWT were tested, along with an inoculation ...
G A, Mayr +4 more
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A replication-defective adenovirus 5 encoding foot-and-mouth disease virus (FMDV) capsid and 3C proteinase coding regions (Ad5-FMDV3CWT) was used to vaccinate swine. A single inoculation utilizing 1 x 10(8) plaque forming units (pfu) or an inoculation of 1 x 10(8) followed by a boost of 5 x 10(8) pfu Ad5-FMDV3CWT were tested, along with an inoculation ...
G A, Mayr +4 more
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Detection of FMDV RNA amplified by the polymerase chain reaction (PCR)
Journal of Virological Methods, 1992Molecular detection of foot-and-mouth disease virus (FMDV) using the polymerase chain reaction (PCR) is a rapid and accurate method. In this study we present PCR for the detection of FMDV RNA in infected BHK cells. Using PCR and two primers selected from the RNA polymerase gene, a conserved sequence in all types and subtypes of FMDV, we were able to ...
Yechiel Becker, Y Becker
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Transcriptomic analysis of porcine PBMCs in response to FMDV infection
Acta Tropica, 2017Foot-and-mouth disease (FMD) is a significant zoonotic infectious disease. It has an important economic impact throughout the world. As well, it is a considerable threat to food security. At present, the molecular mechanism of FMDV infection is not clear to a large extent. Innate immune response is the first line of defense against infectious diseases.
Fu-Rong, Zhao +6 more
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Translation and Replication of FMDV RNA
2005Foot-and-mouth disease virus (FMDV) RNA is infectious. After delivery of the RNA (about 8.3 kb) into the cytoplasm of a cell, the RNA must initially be translated to produce the viral proteins required for RNA replication and for the packaging of the RNA into new virions. Subsequently there has to be a switch in the function of the RNA; translation has
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Journal of Virology, 1994
The G-H loop of VP1 (residues 132 to 159) of foot-and-mouth disease virus (FMDV) is a prominent feature on the virion surface and has an important role in vaccine efficacy, generation of antigenic variants, and cell binding. Using an infectious cDNA of FMDV, we have constructed serotype A viruses in which the G-H loop has been substituted with the ...
E, Rieder +3 more
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The G-H loop of VP1 (residues 132 to 159) of foot-and-mouth disease virus (FMDV) is a prominent feature on the virion surface and has an important role in vaccine efficacy, generation of antigenic variants, and cell binding. Using an infectious cDNA of FMDV, we have constructed serotype A viruses in which the G-H loop has been substituted with the ...
E, Rieder +3 more
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Biochemical characterization of FMDV A10 and A22 subtypes by PAGE and IEF
Comparative Immunology, Microbiology and Infectious Diseases, 1997Both polyacrylamide gel electrophoresis (PAGE) and iso-electric focusing (IEF) have been standardized using the sucrose density gradient purified 146S particles of FMD virus subtypes A10 and A22. Differences in the molecular weights of structural proteins (VP1, VP2 and VP3 of two subtypes (A10 and A22) of FMDV have been revealed in PAGE but no ...
S, Nandi +3 more
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Early steps in FMDV replication: Further analysis on the effects of chloroquine
Virology, 1985We have previously demonstrated that chloroquine and NH4Cl, two well-known lysosomotropic drugs inhibit foot-and-mouth disease virus (FMDV) replication. This fact points to the relevance of an acidic environment during FMDV penetration. In the present report, we show that chloroquine prevents the cell-mediated disruption of 140 S virions into 12 S ...
E C, Carrillo, C, Giachetti, R, Campos
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Developments in biological standardization, 1979
Different commercially available peptone preparations, all derived by enzymatic digestion of meat, were tested for their ability to replace the individual amino acids and polyethylene glycol (PEG)-treated serum in BHK suspended cell culture growth medium.
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Different commercially available peptone preparations, all derived by enzymatic digestion of meat, were tested for their ability to replace the individual amino acids and polyethylene glycol (PEG)-treated serum in BHK suspended cell culture growth medium.
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Investigating the quaternary structure of the FMDV Leader protease
2009Das Maul-und Klauenseuchevirus (MKSV) stellt ein Mitglied der Picornavirus-Familie dar und ist ein kleines, nicht-umhülltes Virus mit einem einzelsträngigen RNA-Genom mit positiver Polarität. Das RNA-Genom wird direkt in ein Polyprotein translatiert, welches anschließend von viralen Proteasen prozessiert wird.
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High selectivity detection of FMDV- SAT-2 using a newly-developed electrochemical nanosensors
Biosensors and Bioelectronics, 2021Heba A Hussein +2 more
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