Concentration- and Time-Dependent Virucidal Responses of Major Transboundary Animal Disease Viruses to Disinfectants. [PDF]
Song S +4 more
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Incubation phase transmission of foot-and-mouth disease virus in cattle: experimental evidence and simulated impacts. [PDF]
Stenfeldt C, Humphreys JM, Arzt J.
europepmc +1 more source
Inactivated Type 'O' Foot and Mouth Disease Virus Encapsulated in Chitosan Nanoparticles Induced Protective Immune Response in Guinea Pigs. [PDF]
Ramya K +6 more
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Integrated multiomics reveals host-virus coadaptation in persistent foot-and-mouth disease virus infection. [PDF]
Wang S +8 more
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DDX56 cooperates with FMDV 3A to enhance FMDV replication by inhibiting the phosphorylation of IRF3
The components of foot-and-mouth disease virus (FMDV) interact with host cellular proteins to promote self-replication and evade the host immune response. Previous studies have shown that FMDV 3A, 2C and 2B proteins interact with host cellular proteins involved in FMDV replication.
, Xiang-Tao Liu
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Picornavirus infection can lead to disruption of nuclear pore traffic, shut-off of cell translation machinery, and cleavage of proteins involved in cellular signal transduction and the innate response to infection. Here, we demonstrated that the FMDV 3C(pro) induced the cleavage of nuclear RNA-binding protein Sam68 C-terminus containing the nuclear ...
Paul Lawrence, Elizabeth Rieder
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Recombinant T7 Phage with FMDV AKT-III Strain VP1 Protein is a Potential FMDV Vaccine
Biotechnology Letters, 2020The capsid protein (VP1) of the foot-and-mouth (FMD) AKT-III strain was expressed on the surface of the T7 phage capsid (AKT-T7 strain) and the potential of AKT-T7 strain as an FMD vaccine was evaluated.The AKT-T7 strain was successfully constructed and was not cytotoxic to BHK-21, MDBK, or sheep kidney cells. The AKT-T7 strain was well phagocytosed by
Chuangfu Chen, Chen Chuangfu
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Pressure-inactivated FMDV: a potential vaccine
Vaccine, 2004Foot-and-mouth disease virus (FMDV) is the causative agent of the foot-and-mouth disease (FMD). Alternative FMD vaccines have been pursued due to important disadvantages of the one currently in use. High hydrostatic pressure (HP) has been observed to inactivate some viruses.
Daniella, Ishimaru +2 more
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Molecular basis of pathogenesis of FMDV
Virus Research, 2003Current understanding of the molecular basis of pathogenesis of foot-and-mouth disease (FMD) has been achieved through over 100 years of study into the biology of the etiologic agent, FMDV. Over the last 40 years, classical biochemical and physical analyses of FMDV grown in cell culture have helped to reveal the structure and function of the viral ...
Peter W, Mason +2 more
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Susceptibility of various FMDV strains to urea
Archives of Virology, 1978Resistance to urea in vitro at 37 degrees C varied for each FMDV strain analysed. The urea marker did not correlate with other markers such as resistance to acid, resistance to acidity or size of plaques under agar on BHK21/13 cells. The resistance to urea of subtypes A24 Cruzeiro, O1 Caseros and C3 Resende varied in accordance with their antigenic ...
R F, Maes, I, Gomes, P, Augé de Mello
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