Results 41 to 50 of about 13,326 (150)

Sclerostin regulates bone morphogenetic protein (BMP) bioavailability through interactions with BMP complexes and fibrillin microfibrils

The FEBS Journal, EarlyView.
Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns, Fady Marcous, Steffen Lütke, Matthias Mörgelin, Philipp Barnowski, Ariane G. Furlan, Nathalie H. Schröder, Bodo Levkau, Sarah Riek, Martin Mollenhauer, Manuel Koch, Gerhard Sengle   +11 more
wiley   +1 more source

Cutaneous lymphomas – an update

Histopathology, EarlyView.
Primary cutaneous lymphomas and lymphoproliferative disorders are defined by integrated clinical, histopathological, immunophenotypic and genetic features as diagnostic criteria also in the 5th edition of the WHO classification of haematolymphoid tumors.
Werner Kempf, Christina Mitteldorf
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

High prolidase levels in patients with Familial Mediterranean Fever (FMF)

, 2020
Introduction. Familial Mediterranean Fever (FMF) is an autoinflammatory disease. Prolidase is a specific imidodipeptidase that plays a role in collagen degradation, and an important role in inflammation and wound healing. Hypoxia-inducible factor-1α (HIF-
Derin Mehmet Emin, Asan Gökmen, Şahin Mehtap, Bayram Meliha, Doğan Halef Okan, Şahin Ali, Asan, Gokmen, Dogan, Halef Okan, Bayram, Meliha, Derin, Mehmet Emin, Sahin, Mehtap, Sahin, Ali   +11 more
core   +1 more source

Association of Treatment‐Related Weight Changes With Functional Impairments, Public Visits, and Future Life Perspectives in Oral Cancer: A Multicenter Study

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to evaluate treatment‐related weight changes in oral cancer and examine their association with functional impairments, public visits, and future life perspectives. Materials and Methods Data from 1359 surgically treated patients were retrospectively analyzed in a multicenter rehabilitation study conducted by the ...
Efthymios Papazacharias, Max Lukas Linderkamp, Stephan Alexander Bettag, Anij von der Gracht, Rijahd Sahmer Boustani, Jan Gaessler, Thomas Lewandowski, Fritjof Lentge, Michael‐Tobias Neuhaus, Gertrud Krüskemper, Nils‐Claudius Gellrich, Philippe Korn, Philipp Jehn   +12 more
wiley   +1 more source

Different intrafamilial clinical presentation of FMF mutation carriers

, 2008
Familial Mediterranean fever (FMF) is a heterogeneous disorder; at present, it is diagnosed using only genetic methods. In the current study, we performed molecular analysis in two families presenting with FMF. In the first family, we report two brothers
Lamnisou, Kleoniki, Kyriakopoulou, Vanessa; id_orcid, Nasioulas, Georgios, Chalevelakis, Georgios, Apostolakis, Ioannis, Koliou, Xeni, Apessos, Angela, Vasilopoulou, Adamantia, Vrakidou, Evfimia   +8 more
core   +3 more sources

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Co‐ingesting whey protein with dual‐source carbohydrate enhances amino acid availability without compromising post‐exercise liver glycogen resynthesis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical overview of the experimental study. The upper‐left panel presents the research question, and the bottom‐left panel provides a schematic overview of the experimental design. The right‐hand panel depicts repetitive spectral data obtained by magnetic resonance spectroscopy, liver glycogen content during the 5 h post ...
Sophie C. Hannon, James McStravick, Libby Henthorn, Stephen J. Bawden, Jonathan C. Y. Tang, Rachel Dunn, Ryosuke Makino, Kenneth Smith, Javier T. Gonzalez, Nathan Hodson, James P. Morton, Aneurin J. Kennerley, Mark A. Hearris   +12 more
wiley   +1 more source

Correction to: P92 chronic arthritis as the only manifestation of FMF in Armenian children

, 2017
Familial Mediterranean Fever (FMF) is the most common inherited auto inflammatory disease, characterized by recurrent, self–limited attacks of fever and aseptic polyserositis.FMF is widespread in Armenia and there is a higher than expected frequency of ...
Gayane Khloyan, Rotraud Saurenmann, Gayane Amaryan   +2 more
core   +1 more source

Willingness‐to‐Pay for Health Insurance in South Asia: A Systematic Review and Meta‐Analysis

Public Health Challenges, Volume 5, Issue 4, December 2026.
Seventeen studies from five South Asian countries were included. The pooled proportion willing to pay for health insurance was 72% (95% CI: 61%–82%), with higher estimates in Bangladesh than India. Age, education, income, occupation, socio‐economic status, healthcare utilisation and healthcare expenditure were commonly associated with willingness‐to ...
Md Fuad Al Fidah, Sayeda Sumaiya Efa, Md Ridwan Islam, Md Abdullah Saeed Khan   +3 more
wiley   +1 more source