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Functional magnetic resonance imaging (fMRI) generates vast amounts of data. The handling, processing, and analysis of fMRI data would be inconceivable without computer-based methods. fMRI neuroinformatics is concerned with research, development, and operation of these methods.
Nielsen, Finn Årup +4 more
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Comprehensive analysis of brain function depends on understanding the dynamics of diverse neural signaling processes over large tissue volumes in intact animals and humans. Most existing approaches to measuring brain signaling suffer from limited tissue penetration, poor resolution, or lack of specificity for well-defined neural events. Here we discuss
Barandov, Ali +2 more
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fMRI adaptation revisited [PDF]
Adaptation has been widely used in functional magnetic imaging (fMRI) studies to infer neuronal response properties in human cortex. fMRI adaptation has been criticized because of the complex relationship between fMRI adaptation effects and the multiple neuronal effects that could underlie them.
Jonas, Larsson +2 more
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Several different techniques allow a functional assessment of neuronal activations by magnetic resonance imaging (fMRI). The by far most influential fMRI technique is based on a local T2*-sensitive hemodynamic response to neuronal activation, also known as the blood oxygenation level dependent or BOLD effect. Consequently, the term 'fMRI' is often used
Haller, Sven, Bartsch, Andreas
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Functional magnetic resonance imaging with blood oxygenation level-dependent (BOLD) contrast has had a tremendous influence on human neuroscience in the last twenty years, providing a non-invasive means of mapping human brain function with often exquisite sensitivity and detail. However the BOLD method remains a largely qualitative approach.
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DC Shifts-fMRI: A Supplement to Event-Related fMRI [PDF]
Event-related fMRI have been widely used in locating brain regions which respond to specific tasks. However, activities of brain regions which modulate or indirectly participate in the response to a specific task are not event-related. Event-related fMRI can't locate these regulatory regions, detrimental to the integrity of the result that event ...
Qiang Li +6 more
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Background: Resting state functional MRI (rs-fMRI) provides many advantages to task-based fMRI in neurosurgical populations, foremost of which is the lack of the need to perform a task. Many networks can be identified by rs-fMRI in a single period of scanning.
ST Lang, B Goodyear, J Kelly, P Federico
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Functional magnetic resonance data are traditionally analyzed on a population level, but new work shows that meaningful information can be extracted from individual subjects.
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Rest-fMRI—A Potential Substitute for Task-fMRI?
Abstract Objective The aim of this study was to assess the reliability of resting-state functional magnetic resonance imaging (rest-fMRI) in mapping language areas for preoperative planning, versus standard task-based techniques, which are at times difficult to perform in clinical settings. Our study also aimed to evaluate the overlap between
Santosh S. Gupta +2 more
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Abstract After an fMRI experiment has been designed and carried out, the resulting data must be passed through various analysis steps before the experimenter can get answers to questions about experimentally-related activations at the individual or multi-subject level.
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