Results 131 to 140 of about 369,066 (296)

Neuroanatomical correlates of neuropsychological dysfunction in pediatric pharmacoresistant epilepsy due to focal cortical dysplasia type II

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Children and adolescents with pharmacoresistant epilepsy (PRE) show marked individual cognitive and emotional variability not fully accounted for by demographic or clinical variables. This exploratory pilot study characterizes neuroanatomical abnormalities and their relationships with neuropsychological functioning in a pediatric ...
Ana Arenivas   +9 more
wiley   +1 more source

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

open access: yesIbrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

open access: yesiNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu   +10 more
wiley   +1 more source

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

open access: yesiNew Medicine, EarlyView.
ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang   +8 more
wiley   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

open access: yesInterdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li   +24 more
wiley   +1 more source

Testing for spatial heterogeneity in functional MRI using the multivariate general linear model [PDF]

open access: yes
Much current research in functional MRI employs multivariate machine learning approaches (e.g., support vector machines) to detect fine-scale spatial patterns from the temporal fluctuations of the neural signal.
Leech, Dennis, Leech, Robert
core  

‘Pre‐Technologies’ and the Lifeworld: Assistive Technologies as ‘Pre‐Technologies’ for Self‐Formation as Freedom

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT This article identifies assistive technologies (ATs) as ‘pre‐technologies’ mediating access to other technologies for disabled subjects (DSs). The motivation is to show that without ATs, DSs cannot be said to have the same level of access to freedom and self‐forming activities as able‐bodied subjects.
Sarel Marais
wiley   +1 more source

Biomarkers of Suicidal Ideation in Depression: Insights From VMHC Analysis and Machine Learning

open access: yesNeuropsychiatric Disease and Treatment
Xinlin Wang,1,* Fei Liu,1,* Xinyi Hu,1 Qiong Zhang,1 Xiaofeng Guan,1 Jiaxin Wu,1 Xiangyun Long,2 Zheng Lu1 1Department of Psychiatry, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China ...
Wang X   +7 more
doaj  

Enhancing spatial cognition through origami training: Insights from brain connectomes

open access: yesJournal of Intelligent Medicine, EarlyView.
Origami training enhances spatial cognition via measurable brain network changes (EEG/eye‐tracking). The mental rotation and folding tasks validate these gains. This low‐cost method offers a scalable intervention for cognitive decline. Abstract Spatial cognition is a key ability of human cognition and intelligence.
Xiuyun Liu   +13 more
wiley   +1 more source

Improving Procedure Completion and Engagement of Neurodivergent Patients in Medical Imaging: A Systematic Review

open access: yesJournal of Medical Radiation Sciences, EarlyView.
Neurodivergent patients face barriers in accessing and engaging with medical imaging services. This systematic review aims to identify strategies in the literature to improve imaging procedure completion among neurodivergent patients. ABSTRACT Introduction Neurodivergent conditions such as autism and attention deficit hyperactivity disorder (ADHD) are ...
Rheann Wickramasinghe, Glenda McLean
wiley   +1 more source

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