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FMRP and MicroRNAs in Neuronal Protein Synthesis
2018Abstract New protein synthesis is critical for learning and memory. The discovery of ribosomes at synapses indicated the potential for local protein synthesis in response to stimulation. miRNAs play a key role in this process as evidenced by their role in normal neuronal development and function and in neurological disease.
Monica C. Lannom, Stephanie Ceman
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Cancer Research
Abstract Our research has uncovered a novel and significant role for Fragile-X-mental-retardation-protein (FMRP) in cancer biology, extending its well-established functions beyond neuronal development. In a recent Science publication (Zeng et al., 2022), we demonstrated that elevated FMRP levels drive immune evasion in various murine and
Simge Yucel +3 more
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Abstract Our research has uncovered a novel and significant role for Fragile-X-mental-retardation-protein (FMRP) in cancer biology, extending its well-established functions beyond neuronal development. In a recent Science publication (Zeng et al., 2022), we demonstrated that elevated FMRP levels drive immune evasion in various murine and
Simge Yucel +3 more
openaire +1 more source
FMRP phosphorylation modulates neuronal translation through YTHDF1
Molecular Cell, 2023Yantao Chen
exaly
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development
Neuron, 2023Xinyu Zhao
exaly
Novel FMRP interaction networks linked to cellular stress
FEBS Journal, 2021Mohamed S Taha +2 more
exaly
FMRP-dependent production of large dosage-sensitive proteins is highly conserved
Genetics, 2022Keegan Flanagan +2 more
exaly
FMRP gains mitochondrial fission control
Nature Cell BiologyCarissa L. Sirois +2 more
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FMRP expression as a potential prognostic indicator in fragile X syndrome
American Journal of Medical Genetics Part A, 1999Flora Tassone +2 more
exaly