Results 271 to 280 of about 50,276 (321)
Some of the next articles are maybe not open access.
Journal of Neurosurgery, 1988
✓ A histologically confirmed case of focal dysplasia of the cerebral cortex is presented. The computerized tomographic, electroencephalographic, pathological, and angiographic findings are discussed with respect to this rare developmental disorder. A review of the literature is presented with a possible etiology for this condition.
D B, Moreland +4 more
openaire +4 more sources
✓ A histologically confirmed case of focal dysplasia of the cerebral cortex is presented. The computerized tomographic, electroencephalographic, pathological, and angiographic findings are discussed with respect to this rare developmental disorder. A review of the literature is presented with a possible etiology for this condition.
D B, Moreland +4 more
openaire +4 more sources
Ultra‐Low Level Somatic Mutations and Structural Variations in Focal Cortical Dysplasia Type II
Annals of Neurology, 2023Brain somatic mutations in mTOR pathway genes are a major genetic etiology of focal cortical dysplasia type II (FCDII). Despite a greater ability to detect low‐level somatic mutations in the brain by deep sequencing and analytics, about 40% of cases ...
Ja Hye Kim +9 more
semanticscholar +1 more source
Archives of Neurology, 2003
Focal cortical dysplasia (FCD) is a type of malformation of cortical development that primarily affects areas of neocortex. It can be identified on conventional magnetic resonance imaging as focal cortical thickening, abnormal gyration, and blurring between gray and white matter, often associated with clusters of heterotopic neurons.
Nobutaka, Arai, Akira, Yagishita
openaire +4 more sources
Focal cortical dysplasia (FCD) is a type of malformation of cortical development that primarily affects areas of neocortex. It can be identified on conventional magnetic resonance imaging as focal cortical thickening, abnormal gyration, and blurring between gray and white matter, often associated with clusters of heterotopic neurons.
Nobutaka, Arai, Akira, Yagishita
openaire +4 more sources
Epilepsia, 2023
Focal cortical dysplasia (FCD) is the most common etiology of surgically‐remediable epilepsy in children. Eighty‐seven percent of patients with FCD develop epilepsy (75% is pharmacoresistant epilepsy [PRE]).
P. Chang +12 more
semanticscholar +1 more source
Focal cortical dysplasia (FCD) is the most common etiology of surgically‐remediable epilepsy in children. Eighty‐seven percent of patients with FCD develop epilepsy (75% is pharmacoresistant epilepsy [PRE]).
P. Chang +12 more
semanticscholar +1 more source
Neocortical development and epilepsy: insights from focal cortical dysplasia and brain tumours.
Lancet Neurology, 2021During the past decade, there have been considerable advances in understanding of the genetic and morphogenic processes underlying cortical malformations and developmental brain tumours. Focal malformations are caused by somatic (postzygotic) variants in
I. Blumcke +5 more
semanticscholar +1 more source
Cortical development and focal cortical dysplasia
Epileptic Disorders, 2003A brief survey of cortical development is presented, focusing on neuronal migration and its alterations. Corticogenesis is achieved through ordered temporospatial steps, via the formation of transient structures, and successive waves of cell proliferation and migration (followed by cell differentiation and maturation), and apoptotic cell death.
BENTIVOGLIO FALES, Marina +5 more
openaire +3 more sources
Focal cortical dysplasia: an update on diagnosis and treatment
Expert Review of Neurotherapeutics, 2021Introduction Focal cortical dysplasias (FCDs) represent the most common etiology in pediatric drug-resistant focal epilepsies undergoing surgical treatment.
R. Guerrini, C. Barba
semanticscholar +1 more source
Clinical Neurophysiology, 2021
OBJECTIVE Reliable localization of the epileptogenic zone is necessary for successful epilepsy surgery. Neurophysiological biomarkers include ictal onsets and interictal spikes.
S. Rampp +12 more
semanticscholar +1 more source
OBJECTIVE Reliable localization of the epileptogenic zone is necessary for successful epilepsy surgery. Neurophysiological biomarkers include ictal onsets and interictal spikes.
S. Rampp +12 more
semanticscholar +1 more source
CCDC22 variants caused X-linked focal epilepsy and focal cortical dysplasia.
SeizureBACKGROUND The CCDC22 gene plays vital roles in regulating the NF-κB pathway, an essential pathway for neuroinflammation, neurodevelopment, and epileptogenesis.
Yu-Lei He +14 more
semanticscholar +1 more source
Seizure Outcome After Surgery for MRI-Diagnosed Focal Cortical Dysplasia
Neurology, 2021Background and Objectives Focal cortical dysplasia (FCD) has been associated with poorer postsurgical seizure outcomes compared to other pathologies. FCD surgical series have been assembled on the basis of a histologic diagnosis, including patients with ...
Anna Willard +5 more
semanticscholar +1 more source