Results 31 to 40 of about 50,276 (321)

A developmental and genetic classification for malformations of cortical development: update 2012. [PDF]

, 2012
Malformations of cerebral cortical development include a wide range of developmental disorders that are common causes of neurodevelopmental delay and epilepsy. In addition, study of these disorders contributes greatly to the understanding of normal brain
Barkovich, A James, Dobyns, William B, Guerrini, Renzo, Jackson, Graeme D, Kuzniecky, Ruben I   +4 more
core   +3 more sources

External validation of automated focal cortical dysplasia detection using morphometric analysis

Epilepsia, 2021
Focal cortical dysplasias (FCDs) are a common cause of drug‐resistant focal epilepsy but frequently remain undetected by conventional magnetic resonance imaging (MRI) assessment.
B. David, J. Kröll-Seger, Fabiane Schuch, J. Wagner, J. Wellmer, F. Woermann, B. Oehl, W. van Paesschen, T. Breyer, A. Becker, H. Vatter, E. Hattingen, H. Urbach, B. Weber, R. Surges, C. Elger, H. Huppertz, T. Rüber   +17 more
semanticscholar   +1 more source

Role of fetal MRI in the evaluation of isolated and non-isolated corpus callosum dysgenesis: results of a cross-sectional study [PDF]

, 2017
PURPOSE: The aims of this study were to characterize isolated and non-isolated forms of corpus callosum dysgenesis (CCD) at fetal magnetic resonance imaging (MRI) and to identify early predictors of associated anomalies.
Antonelli, Amanda, Bernardo, Silvia, Catalano, Carlo, DE VITO, Corrado, Di Meglio, L, Giancotti, Antonella, Manganaro, Lucia, Marchionni, Enrica, Pizzuti, Antonio, Saldari, Matteo, Silvestri, E, Vinci, Valeria   +11 more
core   +1 more source

Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons [PDF]

, 2020
OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is ...
Jansen, Laura A, Joshi, Suchitra, Kapur, Jaideep, Roden, William H   +3 more
core   +2 more sources

Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study

Epilepsia, 2021
Drug‐resistant focal epilepsy is often caused by focal cortical dysplasias (FCDs). The distribution of these lesions across the cerebral cortex and the impact of lesion location on clinical presentation and surgical outcome are largely unknown.
K. Wagstyl, K. Whitaker, A. Raznahan, Jakob Seidlitz, P. Vértes, Stephen T. Foldes, Zachary Humphreys, Wen-han Hu, Jiajie Mo, M. Likeman, Shirin Davies, M. Lenge, Nathan T. Cohen, Yingying Tang, Shan Wang, M. Ripart, A. Chari, M. Tisdall, N. Bargalló, E. Conde-Blanco, J. Pariente, Saül Pascual-Diaz, Ignacio Delgado-Martínez, C. Pérez-Enríquez, Ilaria Lagorio, E. Abela, N. Mullatti, J. O’Muircheartaigh, Katy Vecchiato, Yawu Liu, M. Caligiuri, B. Sinclair, L. Vivash, Anna Willard, J. Kandasamy, A. McLellan, D. Sokol, M. Semmelroch, Ane G. Kloster, Giske Opheim, Clarissa Yasuda, Kai Zhang, K. Hamandi, C. Barba, R. Guerrini, W. Gaillard, X. You, I. Wang, S. González-Ortiz, M. Severino, P. Striano, D. Tortora, R. Kalviainen, A. Gambardella, A. Labate, P. Desmond, Elaine H. Lui, T. O’Brien, J. Shetty, G. Jackson, J. Duncan, G. Winston, L. Pinborg, F. Cendes, J. Cross, T. Baldeweg, S. Adler   +66 more
semanticscholar   +1 more source

Detection superiority of 7 T MRI protocol in patients with epilepsy and suspected focal cortical dysplasia [PDF]

, 2016
In 11 adult patients with suspicion of Focal cortical dysplasia (FCD) on 1.5 T (n = 1) or 3 T (n = 10) magnetic resonance imaging (MRI), 7 T MRI was performed.
Boon, Paul, Buijs, M, Colon, Albert, Hofman, PAM, van Buchem, MA, van de Grond, J, van Osch, MJP   +6 more
core   +3 more sources

Language lateralization mapping (reversibly) masked by non-dominant focal epilepsy: a case report

Frontiers in Human Neuroscience, 2023
Language lateralization in patients with focal epilepsy frequently diverges from the left-lateralized pattern that prevails in healthy right-handed people, but the mechanistic explanations are still a matter of debate.
Belén Abarrategui, Belén Abarrategui, Valeria Mariani, Valeria Mariani, Michele Rizzi, Michele Rizzi, Luca Berta, Pina Scarpa, Flavia Maria Zauli, Flavia Maria Zauli, Flavia Maria Zauli, Silvia Squarza, Paola Banfi, Piergiorgio d’Orio, Piergiorgio d’Orio, Piergiorgio d’Orio, Francesco Cardinale, Francesco Cardinale, Francesco Cardinale, Maria Del Vecchio, Fausto Caruana, Pietro Avanzini, Ivana Sartori   +22 more
doaj   +1 more source

Prevalence and Risk Factors for Pharmacoresistance in Children With Focal Cortical Dysplasia–Related Epilepsy

Neurology, 2022
Background and Objectives Focal cortical dysplasia (FCD) is the most common cause of surgically remediable epilepsy in children. Little is known about the risk factors for the timing and development of pharmacoresistance in this population.
Nathan T. Cohen, P. Chang, X. You, Anqing Zhang, Kathryn A. Havens, C. Oluigbo, M. Whitehead, T. Gholipour, W. Gaillard   +8 more
semanticscholar   +1 more source

Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. [PDF]

, 2014
Autism spectrum disorders (ASDs) are complex and heterogeneous developmental disabilities affecting an ever-increasing number of children worldwide. The diverse manifestations and complex, largely genetic aetiology of ASDs pose a major challenge to the ...
Adamopoulos, Iannis E, Cates, Staci L, Orosco, Lori A, Pleasure, David, Pleasure, Samuel J, Ross, Adam P, Scott, Sean E, Sohn, Jiho, Wu, Dennis, Zarbalis, Konstantinos S   +9 more
core   +2 more sources

Focal cortical dysplasia

Majalah Biomorfologi, 2019
Cortical dysplasia or  focal  cortical dysplasia (FCD) is one of the most common causes of seizures and childhood epilepsy. It is one of some malformation types of cortical development. By using magnetic resonance imaging (MRI) or another radiographic modality, it is not easy to detect its abnormalities.
Purwidyastuti, Desy, Kalanjati, Viskasari Pintoko   +1 more
  +5 more sources