Results 31 to 40 of about 10,901 (243)

Adult-onset Isolated Focal Dystonia: A Comprehensive Review of the Literature [PDF]

Modern Medicine
Dystonia is a rare movement disorder, defined by intermittent or sustained involuntary movements and/or postures. The term can refer both to a clinical syndrome and to a group of primary movement disorders in which dystonia represents the predominant ...
Iulia MITREA, Andreea-Florentina TOMESCU, Ana-Marina HERA-DRAGUT, Ioana-Alexandra DOGARU, Cristiana HERGHELEGIU, Laura DUMITRESCU, Bogdan Ovidiu POPESCU   +6 more
doaj   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Clinical Spectrum of Focal Dystonia in Patients at Tertiary Care Hospital in Karachi: A Cross-Sectional Study

Journal of University College of Medicine and Dentistry
Objective: To describe the clinical patterns and types of focal dystonia among patients presenting to the neurology department of a tertiary care hospital in Karachi. Methodology: This descriptive cross-sectional study was undertaken at Dr. Ruth K. M.
Rabiya Khan, Qamar-Un-Nisa, Sidra Jazil Faruqi, Sumera Rafat Umer, Rabia Iqbal, Wajid Jawaid   +5 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comparison of clinical characteristics of patients with adductor laryngeal dystonia in the focal and segmental types Comparação entre características clínicas de pacientes com distonia laríngea de adução nas formas focal e segmentar

Brazilian Journal of Otorhinolaryngology, 2011
Dystonia is a central motor processing neurological disorder characterized by abnormal, often action-induced, involuntary movements or uncontrolled spasms.
Gustavo Polacow Korn, Miriam Moraes, Luiz Celso Pereira Vilanova, Bruno Teixeira de Moraes, Glaucya Madazio, Marina Padovani, Noemi Grigoletto De Biase   +6 more
doaj   +1 more source

Botulinum Toxin Effects on Sensorimotor Integration in Focal Dystonias

Toxins, 2020
(1) Background: In dystonia, the somatosensory temporal discrimination threshold (STDT) is abnormally increased at rest and higher and longer-lasting during movement execution in comparison with healthy subjects (HS), suggesting an abnormal sensorimotor ...
Maria Ilenia De Bartolo, Nicoletta Manzo, Gina Ferrazzano, Viola Baione, Daniele Belvisi, Giovanni Fabbrini, Alfredo Berardelli, Antonella Conte   +7 more
doaj   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Early Remission in Focal Tardive Dystonia Associated with the Use of Neuroleptic Medication: A Rare Case Report and Review of Literature

Medicine Science, 2015
Tardive dystonia is a movement disorder which develops with twisting of one part of the body or abnormal posture because of severe muscle contractions. The most important factor in the occurrence of tardive dystonia is the use of antipsychotic medication.
Gulsen Aykol, Neslihan Cansel
doaj   +1 more source

Reorganization of the Human Somatosensory Cortex in Hand Dystonia [PDF]

Journal of Movement Disorders, 2012
Background and Purpose: Abnormalities of finger representations in the somatosensory cortex have been identified in patients with focal hand dystonia.
Maria Jose Catalan, Kenji Ishii, William Bara-Jimenez, Mark Hallett   +3 more
doaj   +1 more source

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source