Results 111 to 120 of about 37,393 (310)

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Manifestaciones metafocales de infección odontógena y su relación directa con oftalmopatías Metafocal manifestations of odontogenic infection and their direct relationship with ophthalmopathies

Medisan, 2009
La infección focal se caracteriza por la presencia de un foco séptico primario, que puede localizarse en la región bucofacial e irradiarse a otras partes distales o sistémicas, lo cual impone diagnosticarla adecuada y oportunamente para poder tratarla y ...
José Manuel Díaz Fernández, José Jardón Caballero, Ricardo Pérez Arredondo   +2 more
doaj  

216 Jewish Hospital of St. Louis [PDF]

, 1960
https://digitalcommons.wustl.edu/bjc_216/1047/thumbnail ...

core   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

Advanced Science, EarlyView.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang, Yaodong Gu, Wen Du, Lin Xie, Jinwei Quan, Yu Zhao, Ye Cheng, Zhaonan Wei, Yuanyuan Sha, Yi Wang, Dechao Xu, Xiang Gao, Min Chen, Xiangchen Gu   +13 more
wiley   +1 more source

Intra- and Extra-articular Features of Temporomandibular Joint Ankylosis in the Cat (Felis catus). [PDF]

, 2020
Temporomandibular joint (TMJ) ankylosis is an uncommon clinical entity in human and veterinary medicine. However, the condition is severely debilitating and is life-limiting if not treated. This study sought to characterize the intra- and extra-articular
Arzi, B, Garcia, T, Hatcher, DC, Vapniarsky, N, Verstraete, FJM, Zavodovskaya, R   +5 more
core  

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Impacto social de la estrategia para disminuir la incidencia de celulitis facial odontógena: Matanzas Social impact of the strategy to determine the incidence of odontogenic facial cellulites: Matanzas

Revista Médica Electrónica, 2009
La celulitis facial odontógena es relativamente frecuente, puede convertirse en un grave riesgo vital cuando el tratamiento no es adecuado. Su incidencia es un problema de salud, demuestra que las medidas y acciones de promoción y prevención de salud no ...
María Teresa Lima Reyna
doaj  

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Cryptogenic Perirolandic Brain Abscess in an Otherwise Healthy Young Man

Clinical Case Reports
A previously healthy 19‐year‐old male presented with 1 day of transient right‐sided weakness, numbness, and gait disequilibrium after recent self‐limited sinonasal symptoms and minor nasal trauma with epistaxis.
Mazen Taman, Carl Porto, Jean‐Luc Lewis, Dimitrios Farmakiotis, Athar N. Malik   +4 more
doaj   +1 more source