Results 101 to 110 of about 224,179 (297)

Association between footwear use and neglected tropical diseases : a systematic review and meta-analysis [PDF]

, 2014
BACKGROUND: The control of neglected tropical diseases (NTDs) has primarily focused on preventive chemotherapy and case management. Less attention has been placed on the role of ensuring access to adequate water, sanitation, and hygiene and personal ...
Brooker Simon J., Khizar Rafique (659569), Knopp, S., Sara Tomczyk (177762), Rafique, Khizar, Utzinger, Jürg, Simon J. Brooker, Deribe, K., Deribe Kebede, Rafique Khizar, Stefanie Knopp, Utzinger Jürg, Sara Tomczyk, Deribe, Kebede, Simon J. Brooker (139017), Kebede Deribe, Tomczyk, Sara, Jürg Utzinger, Hannah Clark (659568), Clark Hannah, Davey, G., Davey Gail, Kebede Kassaye (4465078), Simon J Brooker, Utzinger, J., Jürg Utzinger (39609), Gail Davey (4462069), Brooker, Simon J, Brooker, S. J., Clark, H., Stefanie Knopp (108848), Tomczyk, S., Clark, Hannah, Tomczyk Sara, Simon J Brooker (16181729), Kebede Deribe (95495), Rafique, K., Gail Davey (155158), Knopp, Stefanie, Gail Davey, Khizar Rafique, Knopp Stefanie, Hannah Clark, Davey, Gail   +43 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A rare presentation of blastomycosis as a multi-focal infection involving the spine, pleura, lungs, and psoas muscles in a Saudi male patient: a case report. [PDF]

BMC Infect Dis, 2022
Eldaabossi S, Saad M, Aljawad H, Almuhainy B.   +3 more
europepmc   +1 more source

Perfil epidemiológico e clínico de pacientes com a coinfecção HIV e toxoplasmose cerebral [PDF]

, 2004
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Scalco, Gabriel
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Neonatal infection with MCMV results in a focal encephalitis with global deficits within the cerebellum.

, 2013
A. Expression of immediate early gene 1, protein pp89 (IE-1) (green) in the cerebellum, a non-structural protein encoded by MCMV very early in infection, PND8, 60×.
Kate Kosmac (386527), Glenn R. Bantug (386528), William J. Britt (238149), Ester P. Pugel (386529), Djurdjica Cekinovic (386530), Stipan Jonjic (139671)   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Stepwise Approach to Managing Bilateral Maxillary Sinus Tracts: A Case Report

Clinical Case Reports
This case report describes a rare presentation of bilateral intraoral sinus tracts of odontogenic origin associated with a maxillary right first molar (Universal #3).
Ali Chamani, Maryam Forghani, Reza Shakiba, Arsalan Shahri   +3 more
doaj   +1 more source

Early Tonsillectomy for Dual Remission of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis Syndrome and Immunoglobulin A Nephropathy: A Case Report

Kidney Medicine
Despite sharing tonsillar immune dysregulation as a common pathogenic mechanism, concurrent presentation of periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome with immunoglobulin A (IgA) nephropathy (IgAN) remains ...
Daishi Hirano, Kensuke Joh, Shiko Honma, Ryoko Sakaguchi, Aya Saito, Yuna Hiwatari, Shiho Yoshizawa, Yosuke Shoji, Haruhide Sakaguchi, Chisato Umeda, Saori Miwa, Akira Ito   +11 more
doaj   +1 more source