Results 141 to 150 of about 224,179 (297)

Annual proportions of bacteraemia episodes captured by ICD-10 or NOMESCO codes designating “Bacteraemia/sepsis” or “Focal infection”, 2000–2011.

open access: yes, 2015
Annual proportions of bacteraemia episodes captured by ICD-10 or NOMESCO codes designating “Bacteraemia/sepsis” or “Focal infection”, 2000–2011.
Jenny Dahl Knudsen (449844)   +10 more
core   +1 more source

Descending mediastinitis: a review

open access: yesSão Paulo Medical Journal
CONTEXT: Mediastinitis is an inflammation of connective tissue that involves mediastinal structures. When the condition has an infectious origin located in the cervical or oral region, it is termed "descending mediastinitis" (DM).
Luis Marcelo Inaco Cirino   +2 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Mycobacterium ulcerans infection: a rediscovered focus in the Capricorn coast region of central Queensland

open access: yes, 2006
Mycobacterium ulcerans is an environmental pathogen with a global geographic distribution and focal disease clusters. The World Health Organization considers M. ulcerans infection to be of increasing global importance, particularly in West Africa.
Woods, M, Francis, GD, Whitby, M
core  

Focal Eosinophilic Myositis of the Hand Presenting as a Refractory Pyogenic Infection

open access: yes, 2019
Eosinophilic myositis is a rare disorder in which eosinophils infiltrate muscle and supporting connective tissue structures. The disorder can be localized or diffuse, and it may be associated with various systemic features resembling autoimmune disease ...
고영도, 노영학
core   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Antibody-Functionalized MoS2 Nanosheets for Targeted Photothermal Therapy of Staphylococcus aureus Focal Infection. [PDF]

open access: yesFront Bioeng Biotechnol, 2019
Zhang Y   +8 more
europepmc   +1 more source

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