Results 41 to 50 of about 217,042 (254)

New alternatives for the treatment of uncomplicated urinary tract infection, presentation of 2 clinical cases [PDF]

open access: yesRevista Colombiana de Nefrología, 2018
The current perspective on the management of infectious diseases is a challenge for clinicians, because while new antibiotics are developed, bacteria improves its resistance system.
Andrés F. Reyes   +1 more
doaj  

FACTORS OF MUTUAL AGGRAVATION OF MULTIPLE CHRONIC FOCI OF INFECTION AND GENERALIZED PERIODONTITIS

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2018
Introduction. The Inflammatory Diseases of the Parodont (IDP) of generalized character are closely connected petrogenetically with internal pathology and are a serious factor of its burdening, forming a negative comorbidity.
I. A. Gorbachevа   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Predictors of infectious foci on FDG PET/CT in Staphylococcus aureus bacteremia

open access: yesScientific Reports, 2023
We looked for predicting factors for the detection of infectious foci on 18F-fluorodeoxyglucose-positron emission tomography in combination with computed tomography (FDG PET/CT) among patients with Staphylococcus aureus bacteremia (SAB) who participated ...
Nesrin Ghanem-Zoubi   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Extra-Palmoplantar Lesions of Palmoplantar Pustulosis: Underrecognized but Important Manifestation

open access: yesIndian Journal of Dermatology
Background: Patients with palmoplantar pustulosis (PPP) rarely develop scaly erythematous and/or pustular lesions on sites other than the palms and soles, such as the dorsa of the feet, lower legs, knees, elbows, buttocks and trunk.
Toshiyuki Yamamoto
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Plasma ddPCR for etiological diagnosis of focal bacterial infections

open access: yesFrontiers in Medicine
BackgroundPlasma droplet digital polymerase chain reaction (ddPCR) has been used for pathogen detection and has shown good diagnostic value, but no studies have yet demonstrated its application in focal infections. Herein a pilot study using plasma ddPCR
Yongfeng Zhang   +22 more
doaj   +1 more source

Estado actual de la infección focal y del éxito del tratamiento endodóntico //Current status of focal infection and the success of endodontic treatment

open access: yesRevista de la Asociación Odontológica Argentina, 2023
Resumen Frente a la difusión en medios de comunicación de medias verdades con enunciados alarmantes y anticientíficos, este editorial busca revisar las bases científicas para determinar el comportamiento clínico.
Manoel Machado
doaj   +1 more source

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