Focal Point Theory Models for Dissecting Dynamic Duality Problems of Microbial Infections [PDF]
Extending along the dynamic continuum from conflict to cooperation, microbial infections always involve symbiosis (Sym) and pathogenesis (Pat). There exists a dynamic Sym‐Pat duality (DSPD) in microbial infection that is the most fundamental problem in infectomics. DSPD is encoded by the genomes of both the microbes and their hosts.
Huang, S.-H., Zhou, W., Jong, A.
openaire +2 more sources
A transcriptomic investigation of handicap models in sexual selection [PDF]
We are grateful to D. Calder and T. Helps for access to study sites, and G. Murray-Dickson and M. Oliver for help with fieldwork and comments on manuscript drafts. This work was funded by NERC grant NE/D000602/1 (SBP), a NERC advanced fellowship (FM) and
Martinez-Padilla, Jesus +5 more
core +1 more source
Germs, Dr. Billings, and the Theory of Focal Infection [PDF]
Our understanding of infectious diseases continues to expand rapidly, and has led to the realization that microorganisms are responsible for, or at least contribute to, numerous diseases that were never before associated with infectious etiologies. However, a review of medical history reminds us that this is not so novel an idea.
openaire +2 more sources
A proposed role for sepsis in the pathogenesis of myocardial calcification [PDF]
Myocardial calcification is a rare and life-threatening condition that is a recognised complication of ischaemic heart disease, cardiac surgery, rheumatic fever and myocarditis.
AROMATARIO, MARIAROSARIA +7 more
core +1 more source
The gateway theory: bridging neural and immune interactions in the CNS
The central nervous system (CNS) is considered an immune-privileged tissue protected by a specific vessel structure, the brain-blood barrier (BBB). Upon infection or traumatic injury in the CNS, the BBB is breached, and various immune cells are recruited
Daisuke eKamimura +9 more
doaj +1 more source
Identifying spatial invasion of pandemics on metapopulation networks via anatomizing arrival history [PDF]
Spatial spread of infectious diseases among populations via the mobility of humans is highly stochastic and heterogeneous. Accurate forecast/mining of the spread process is often hard to be achieved by using statistical or mechanical models.
Li, Xiang, Wang, Jian-Bo, Wang, Lin
core +2 more sources
Reaction-diffusion spatial modeling of COVID-19: Greece and Andalusia as case examples [PDF]
We examine the spatial modeling of the outbreak of COVID-19 in two regions: the autonomous community of Andalusia in Spain and the mainland of Greece. We start with a 0D compartmental epidemiological model consisting of Susceptible, Exposed, Asymptomatic,
Cuevas-Maraver, J. +4 more
core +2 more sources
Update on Focal Infection Management: A Czech Interdisciplinary Consensus
Background: The focal infection theory has been used to explain several chronic systemic diseases in the past. Systemic diseases were thought to be caused by focal infections, such as caries and periodontal diseases, and dentists were held responsible ...
Vojtěch Peřina +3 more
doaj +1 more source
One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases [PDF]
Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most ...
Adamo +135 more
core +4 more sources
DENDRITIC CELL DIFFERENTIATION BLOCKED BY PRIMARY EFFUSION LYMPHOMA-RELEASED FACTORS IS PARTIALLY RESTORED BY INHIBITION OF P38 MAPK [PDF]
To better understand the molecular mechanisms underlying the dendritic cell (DC) defects in cancer, we analyzed which signaling pathway is implicated in the abnormal monocyte differentiation into DC determined by the presence of Primary effusion lymphoma
CIRONE, Mara +6 more
core +2 more sources

