Results 51 to 60 of about 89,950 (274)
Vertical and horizontal transmission of plant viruses: two extremes of a continuum?
npj VirusesParasites have a variety of mechanisms to be transmitted to new susceptible hosts, which can be largely grouped in two main modes: vertical (i.e., from parents to the offspring) and horizontal (i.e., between hosts regardless of descent).
Lucía García-Ordóñez, Israel Pagán
doaj +1 more source
Goal conflict, goal facilitation, and health professionals' provision of physical activity advice in primary care : An exploratory prospective study [PDF]
, 2011 Peer reviewedPublisher ...
Campbell, Neil C +3 more
core +5 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Chaotic provinces in the kingdom of the Red Queen
, 2017 The interplay between parasites and their hosts is found in all kinds of species and plays an important role in understanding the principles of evolution and coevolution.
Gokhale, Chaitanya S. +2 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Studies on the rejection of the transplanted homologous dog liver. [PDF]
, 1961 Dogs in which livers have been replaced with hepatic homografts usually die in 5 to 10 days. Liver metabolism is not detectably abnormal at first, but gradual deterioration of function commences on the fourth or fifth day.
BROCK, DR +3 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Efficacy of Probiotics for Reducing the Incidence of Lameness in Broilers Grown on Wire Flooring [PDF]
, 2013 Growing broilers on wire flooring provides an excellent experimental model for reproducibly triggering significant levels of lameness. In Pilot Study #1 using broilers from Line C grown on wire flooring, adding the Biomin probiotic PoultryStar® to the ...
Stark, John Matthew
core +2 more sources
Comparison of two models of tethered motion [PDF]
, 2019 We consider a random walker whose motion is tethered around a focal point. We use two models that exhibit the same spatial dependence in the steady state but widely different dynamics.
Chase, Matt +2 more
core +3 more sources