Results 101 to 110 of about 810,493 (346)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Some Aspects about Seismology of 2012 August 11 Ahar-Vaezaghan (Azarbayjan, NW of Persia) Earthquakes Sequences [PDF]
Journal of Sciences, Islamic Republic of Iran, 2013 In 2012 August 11 (12:23 UTC) a moderate earthquake with MW=6.4 (USGS) occurred between Ahar and Varzaghan towns in Azarbayjan Province at northwest of Iran. After eleven minutes another earthquake shook the area with MW=6.2 (USGS).
M. Nemati
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Геодинамика и тектонофизика, 2020 The study is focused on searching for spatial regularities in the occurrence of earthquake hypocenters in different geological settings in Northern Armenia. Tectonic-geomorphological indices are applied to define the tectonic activity of blocks composing
K. S. Ghazaryan, R. S. Sargsyan
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
SEISMOTECTONIC DEFORMATION OF THE LITHOSPHERE IN THE PAMIR AND ADJACENT TERRITORIES
Геодинамика и тектонофизика, 2020 В работе исследована область Памира и Тянь-Шаня, которая является зоной внутриконтинентальных столкновений и представляет большой интерес для изучения геодинамических процессов, протекающих в земной коре и литосфере. Указанная область исследована методом
N. A. Sycheva, A. N. Mansurov
doaj +1 more source
Downward Determination in Semiotic Multi-level Systems [PDF]
, 2012 Peirce's pragmatic notion of semiosis can be described in terms of a multi-level system of constraints involving chance, efficient, formal and final causation. According to the model proposed here, law-like regularities, which work as boundary conditions
El-Hani, Charbel, Queiroz, Joao
core
Dynamic Mechanisms of Neocortical Focal Seizure Onset
PLoS Computational Biology, 2014 Recent experimental and clinical studies have provided diverse insight into the mechanisms of human focal seizure initiation and propagation. Often these findings exist at different scales of observation, and are not reconciled into a common understanding. Here we develop a new, multiscale mathematical model of cortical electric activity with realistic
Wang Y, Goodfellow M, Taylor PN, Baier G
openaire +6 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Focal Mechanism and Source Parameters Analysis of Mining-Induced Earthquakes Based on Relative Moment Tensor Inversion. [PDF]
Int J Environ Res Public Health, 2022 Cao A +6 more
europepmc +1 more source