Results 101 to 110 of about 321,758 (264)
Dizhen xuebao通过初至P震相定位法测定了2021年固原震群中ML≥3.0地震的震源深度，同时根据多阶段定位和微震匹配定位方法对该震群序列进行了重定位，基于Snoke方法和HASH方法计算了震群序列中ML≥2.8地震的震源机制解，并根据gCAP方法反演了震群中最大的地震即2021年6月22日固原ML3.6地震的震源机制解及矩心深度，确定了ML≥2.8地震基于各种方法所得震源机制的中心解，然后根据重定位结果拟合了断层面，最后初步分析了固原震群的发震构造。结果表明：微震检测到901次ML0.0以上地震事件 ...
Yingcai Xu, Xianwei Zeng, Guofu Luo
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Earth Sciences Research Journal, 2002 <p class="MsoNormal" style="line-height: normal; margin: 0cm 0cm 0pt; mso-layout-grid-align: none;"><span style="font-family: ";Arial";,";sans-serif";; font-size: 12pt; mso-ansi-language: EN-US;" lang="EN-US">Earthquake focal solutions can ...
Huerfano Moreno Victor A.
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Study on Microseismic Monitoring of Landslide Induced by Blasting Caving
Applied SciencesThis study focuses on the monitoring and early warning of landslide hazards induced by blasting caving in the Shizhuyuan polymetallic mine. A 30-channel microseismic monitoring system was deployed to capture the spatiotemporal characteristics of rock ...
Fuhua Peng, Weijun Wang
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source