Results 121 to 130 of about 4,240,767 (303)
Dizhen xuebao通过初至P震相定位法测定了2021年固原震群中ML≥3.0地震的震源深度，同时根据多阶段定位和微震匹配定位方法对该震群序列进行了重定位，基于Snoke方法和HASH方法计算了震群序列中ML≥2.8地震的震源机制解，并根据gCAP方法反演了震群中最大的地震即2021年6月22日固原ML3.6地震的震源机制解及矩心深度，确定了ML≥2.8地震基于各种方法所得震源机制的中心解，然后根据重定位结果拟合了断层面，最后初步分析了固原震群的发震构造。结果表明：微震检测到901次ML0.0以上地震事件 ...
Yingcai Xu, Xianwei Zeng, Guofu Luo
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Massive focal mechanism solutions from deep learning in West Texas
The focal mechanism provides seismological constraints on the geological faults that generate the passive seismicity and thus is important for regional seismotectonic research.
Zhang, Fangxue +7 more
core +1 more source
Modelling stromal FAK regulation of tumour growth, angiogenesis and progression [PDF]
, 2012 PhDThe growth of tumours within a whole organism depends on the tumour microenvironment. This involves both resident stromal cells, such as endothelial cells and fibroblasts, and also bone marrow derived stromal cells.
Batista, Silvia
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Up-to-date earthquake and focal mechanism solutions datasets for the assessment of seismic hazard in the vicinity of the United Arab Emirates. [PDF]
Data Brief, 2020 Sawires R +3 more
europepmc +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Harnessing the Power of Focal Points To Measure Social Agreement [PDF]
This paper reports results from an application of Thomas Schelling’s (1960) concept of a focal point to the measure of social agreement on the received tone of media content.
Stuart Soroka, Jim Engle-Warnick
core