Results 221 to 230 of about 810,493 (346)

MINOCA (Myocardial Infarction With Non-obstructive Coronary Arteries) Due to Diffuse Coronary Microvascular Dysfunction in a Patient With Systemic Autoimmune Disease and Chronic Kidney Disease. [PDF]

Cureus
Kamboj T, Gill SS, Chopra N, Wander GS.
europepmc   +1 more source

MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification

, 2017
Mark W. Zimmerman, Yu Liu, Shuning He, Adam D. Durbin, Brian J. Abraham, John Easton, Ying Shao, Beisi Xu, Shizhen Zhu, Xiaoling Zhang, Zhaodong Li, Nina Weichert‐Leahey, Richard A. Young, Jinghui Zhang, A. Thomas Look   +14 more
openalex   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Pickering Syndrome Physiology from Focal Intrarenal Segmental Renal Artery Stenosis: An Under Recognized Cause of Recurrent Hypertensive Emergencies. [PDF]

J Brown Hosp Med
Donkor DKA, Abebe R, Barremkala R, Adrejiya P, Chandra M, Dutta G.   +5 more
europepmc   +1 more source

Local stress concentration in the seismic belt along the Japan Sea coast inferred from precise focal mechanisms: Implications for the stress accumulation process on intraplate earthquake faults [PDF]

, 2009
Rie Kawanishi, Yoshihisa Iio, Yohei Yukutake, Takuo Shibutani, Hiroshi Katao   +4 more
openalex   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Insights into the seismogenesis and tectonic implications of an isolated intraplate earthquake (M4.0) on February 17, 2025, in Delhi. [PDF]

Sci Rep
Prajapati SK, Bhattacharjee S, Pandey AK, Singh RK, Mishra OP.   +4 more
europepmc   +1 more source

Study on three independent parameters of focal mechanism solution [PDF]

, 2017
Qi Li, Kai Tan
openalex   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Defocused illumination with beam-shaping condenser for uniform wide-field X-ray imaging. [PDF]

J Synchrotron Radiat
Zhang K, Luo Y, Di Y, Guo C, Li C, He M, Zhang C, Peng F, Liu W, Wu Z, Guan Y, Tian Y, Liu G.   +12 more
europepmc   +1 more source