Results 281 to 290 of about 810,493 (346)

An FAK Kinase/Scaffold Mode-Switch in Dormancy and Resistance. [PDF]

Cancers (Basel)
Sun C, Feng Q, Zhao Y, Dong Q, Bi L.
europepmc   +1 more source

The importance of nodal plane orientation diversity for earthquake focal mechanism stress inversions

Lund Snee, Jens-Erik, Beauce, Eric, Teran, Orlando J.   +2 more
openalex   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

EM-YOLO: high-precision electronic component detection via multi-scale attention and dynamic feature fusion. [PDF]

Sci Rep
Xu Z, Han J, Qin H, Gao K, Xie K, He J.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Fault diagnosis for pump equipment based on transfer learning: the domain generalization method. [PDF]

Sci Rep
Wang W, Zhao X, Zhang Y, Tan T, Jiang L, Wang C, Zhang L.   +6 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Crop classification method for multi-temporal remote sensing imagery based on a (3 + 2)D SAFPN. [PDF]

Front Plant Sci
Sun Y, Zhao T, Zhang Y, Yu X, Zhang L, Bai Y.   +5 more
europepmc   +1 more source

Complex <i>de novo</i> tetrasomy and trisomy of 2p22.2 involving <i>EIF2AK2</i> in a child with global developmental delay: a case report and literature review. [PDF]

Front Pediatr
Wang J, Duan X, Xu C, Song T, Shen D, Fang F.   +5 more
europepmc   +1 more source

'Carotid spells' - transient focal neurological episodes associated with convexity subarachnoid haemorrhage in severe ipsilateral extracranial internal carotid artery stenosis: a case report and concise literature review. [PDF]

BMC Neurol
Nemes JN, Ferencz E, Klivenyi P, Szalardy L.   +3 more
europepmc   +1 more source