Results 291 to 300 of about 810,493 (346)

Reversible, Noninflammatory ST-Segment Elevation in Cardiac Tamponade. [PDF]

JACC Case Rep
Zhan ZQ.
europepmc   +1 more source

The brain imaging feature-related gene NRP2 drives the malignant progression of glioblastoma through the FAK pathway: a Mendelian randomization study. [PDF]

Transl Oncol
Li Y, Que J, Xia Y, Wang L, Zhang P, Cheng Z, Gao B.   +6 more
europepmc   +1 more source

Broad tunability of ultrasonic tweezer for multi‑droplet manipulation. [PDF]

Microsyst Nanoeng
Yuan Z, Chu J, Lu C, Wang X, Li W, Zhang L, Liu Y.   +6 more
europepmc   +1 more source

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Mechanisms of Focal Adhesion Kinase Regulation

Current Cancer Drug Targets, 2005
Focal adhesion kinase (FAK) is a tyrosine kinase whose phosphorylation state and activity is tightly linked to cell adhesion to the extracellular matrix through integrin receptors. FAK's regulation by adhesion places it in a key position to be able to influence cellular events that are either dependent on cell adhesion like cell proliferation and ...
Lee Ann, Cohen, Jun-Lin, Guan
openaire   +2 more sources

53BP1: function and mechanisms of focal recruitment

Biochemical Society Transactions, 2009
53BP1 (p53-binding protein 1) is classified as a mediator/adaptor of the DNA-damage response, and is recruited to nuclear structures termed foci following genotoxic insult. In the present paper, we review the functions of 53BP1 in DNA-damage checkpoint activation and DNA repair, and the mechanisms of its recruitment and activation following DNA damage.
FitzGerald, Jennifer E., Grenon, Muriel, Lowndes, Noel F.   +2 more
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Physiological Mechanisms of Focal Epileptogenesis

Epilepsia, 1985
Summary: The key elements in the development of epileptogenesis appear to be the capacity of membranes in some (pacemaker) neurons to develop intrinsic burst discharges, the presence of disinhibition, and the proper excitatory synaptic circuitry. It is likely that the relative role of each of these processes will differ at different sites in the ...
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Focal Cerebral Ischemia: Mechanisms

2007
Hypothermia can be neuroprotective when applied during or after focal cerebral ischemia. Its neuroprotective effect is especially robust in the laboratory where it has been shown to ameliorate many of the damaging effects of cerebral ischemia. Most laboratory research on therapeutic cooling in stroke models has been conducted in rodent models of ...
Hyung Soo Han, Midori A. Yenari
openaire   +1 more source