Results 131 to 140 of about 6,812,052 (298)
地球与行星物理论评Do large caves exist deep underground? Through seismological investigations, we speculate the existence of a large geological cave about 7 km beneath the surface.
Tingxiao Xue, Liang Wang
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Automatic Determination of Focal Mechanism Solution Using Initial Motion Polarity of P Waves.
Papers in Meteorology and Geophysics, 2002 自動的に、P波の初動極性を取得し、発震機構解を決定し、十分な精度で発震機構解が決定できているか否かを判別する手法を提案した。P波の初動極性を取得する際には、まず、ベッセルバンドパスフィルタを適用し、次に、ARモデルを用いてP波の初動到達時を得、ARフィルタを適用した。発震機構解の決定には、グリッドサーチによる手法を用いた。十分な精度で発震機構解が決定できているか否かを判別するために、解の安定性、過去に発生した地震の発震機構解等から総合的に判断し、発震機構解の決定精度の評価を行った。気象庁によって読みとられた初動極性の70%が、本手法を適用することによって得られた。また、両者でくい違った験測を行っているのは全体の3.5%以下であり、十分な精度で初動極性の自動験測が行われた。さらに ...
openaire +2 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Harnessing the Power of Focal Points To Measure Social Agreement [PDF]
This paper reports results from an application of Thomas Schelling’s (1960) concept of a focal point to the measure of social agreement on the received tone of media content.
Stuart Soroka, Jim Engle-Warnick
core
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
An enhanced focal mechanism catalog of induced earthquakes in Weiyuan, Sichuan
[updating based on reviews] It includes predictions from PhaseNet+, earthquake, and focal mechanism catalogs based on a local dense seismic array deployed in Weiyuan, Sichuan during 2015 ...
Song, Junhao
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source