Results 1 to 10 of about 80,952 (305)

The Role of Excitability and Network Structure in the Emergence of Focal and Generalized Seizures

Frontiers in Neurology, 2020
Epileptic seizures are generally classified as either focal or generalized. It had been traditionally assumed that focal seizures imply localized brain abnormalities, whereas generalized seizures involve widespread brain pathologies.
Marinho A. Lopes, Marinho A. Lopes, Marinho A. Lopes, Marinho A. Lopes, Marinho A. Lopes, Leandro Junges, Leandro Junges, Leandro Junges, Leandro Junges, Leandro Junges, Wessel Woldman, Wessel Woldman, Wessel Woldman, Wessel Woldman, Wessel Woldman, Marc Goodfellow, Marc Goodfellow, Marc Goodfellow, John R. Terry, John R. Terry, John R. Terry, John R. Terry, John R. Terry   +22 more
doaj   +4 more sources

Non-ketotic hyperglycaemia induced occipital reflex focal seizures [PDF]

Heliyon, 2023
A myriad of neurological manifestations can occur in association with ketotic and non ketotic hyperglycaemic states. Contrary to diabetic coma, which is a universal complication under relatively established metabolic circumstances, the pathophysiology ...
Helena Buque, Deise Catamo, Catarina Felix, Ana André, Inês Gil, Hipólito Nzwalo   +5 more
doaj   +4 more sources

Slow and fast cortical cholinergic arousal is reduced in a mouse model of focal seizures with impaired consciousness [PDF]

Cell Reports
Summary: Patients with focal temporal lobe seizures often experience loss of consciousness associated with cortical slow waves, like those in deep sleep.
Lim-Anna Sieu, Shobhit Singla, Jiayang Liu, Xinyuan Zheng, Abdelrahman Sharafeldin, Ganesh Chandrasekaran, Marcus Valcarce-Aspegren, Ava Niknahad, Ivory Fu, Natnael Doilicho, Abhijeet Gummadavelli, Cian McCafferty, Richard B. Crouse, Quentin Perrenoud, Marina R. Picciotto, Jessica A. Cardin, Hal Blumenfeld   +16 more
doaj   +2 more sources

Pitfalls of using video‐EEG for a trial endpoint in children aged <4 years with focal seizures [PDF]

Annals of Clinical and Translational Neurology
Objective Double‐blind, randomized, and placebo‐controlled trial SP0967 (NCT02477839/2013‐000717‐20) did not demonstrate superior efficacy of lacosamide versus placebo in patients aged ≥1 month to
Ali Bozorg, Cynthia Beller, Lori Jensen, Alexis Arzimanoglou, Catherine Chiron, Dennis Dlugos, John Gaitanis, James W. Wheless, Carrie McClung   +8 more
doaj   +2 more sources

Vagus nerve stimulation for focal seizures. [PDF]

Cochrane Database Syst Rev, 2022
This is an updated version of the Cochrane Review published in 2015. Epilepsy is a chronic neurological disorder, characterised by recurring, unprovoked seizures. Vagus nerve stimulation (VNS) is a neuromodulatory treatment that is used as an adjunctive therapy for treating people with drug-resistant epilepsy.
Panebianco M, Rigby A, Marson AG.
europepmc   +3 more sources

Seizure Cycles in Focal Epilepsy

JAMA Neurology, 2021
Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our knowledge, the prevalence and patterns of seizure cycles are unknown.To establish the prevalence, strength, and temporal patterns of seizure cycles over timescales of hours to years.This retrospective cohort study analyzed data from continuous intracranial ...
Grau Leguia, Marc, Andrzejak, Ralph Gregor, Rummel, Christian, Fan, Joline M., Mirro, Emily A., Tcheng, Thomas K., Rao, Vikram R., Baud, Maxime O.   +7 more
openaire   +4 more sources

Focal seizures during adrenocorticotropic hormone therapy in a school-aged boy: a case report

Journal of Medical Case Reports, 2022
Background Adrenocorticotropic hormone therapy for infantile spasms, including West syndrome, has been previously reported to induce seizures. We present the findings for a school-aged child with epilepsy who developed new focal seizures during ...
Yoshitaka Ota, Shuichi Shimakawa, Hikaru Tsuda-Kitahara, Miho Fukui, Mitsuru Kashiwagi, Akira Ashida   +5 more
doaj   +1 more source

Stroke-related early seizures: clinical and neurophysiological study in a sample of Egyptian population

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023
Background Available data collected from patients of different types of acute cerebrovascular strokes can detect risk factors, clinical data (including semiology of seizures), EEG findings and functional outcome of these patients.
Aya Taha Mohamed, Mahmoud Hemeda El Rakawy, Yousry Abo Elnaga Abdelhamid, Ahmed Mohammed Hazzou, Mona Mokhtar Wahid el din   +4 more
doaj   +1 more source

Cases with parietal and occipital lobe epilepsies

Acta Epileptologica, 2019
Background For seizures emerging from the posterior cortex it can be a challenge to differentiate if they belong to temporal, parietal or occipital epilepsies. Sensoric auras like visual phenomena may occur in all of these focal epilepsies.
Hermann Stefan
doaj   +1 more source

Efficacy and tolerability of eslicarbazepine acetate as monotherapy in patients of newly diagnosed focal epilepsy

European Psychiatry, 2021
Introduction Eslicarbazepine Acetate, a novel anti-epileptic drug has been approved as monotherapy in focal onset seizures, with/without secondary generalization in adults.
S. Saxena, S. Singh
doaj   +1 more source