Results 91 to 100 of about 14,995 (285)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

La Focalis-action : Des savoirs narratifs aux faires vidéoludiques

open access: yesSciences du Jeu, 2018
This essay deals with one of the key concepts in narratology, namely the focalization. It will present a quick overview of the theories in literary and film studies, starting with Gerard Genette who first introduced the notion.
Hugo Montembeault, Bernard Perron
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Å fortelle gjennom traumer

open access: yesNorsk Litteraturvitenskapelig Tidsskrift, 2018
Telling through trauma. Trauma representation in Marguerite Duras' Emily L. This article discusses how psychological trauma can be represented in literature and, more specifically, how it is represented in Marguerite Duras’ novel
Kaisa Hoel
doaj   +1 more source

Scripted bodies: reading the spectacle of Jacob wrestling the Angel [PDF]

open access: yes, 2012
This article argues that by reading the spectacle of Jacob’s struggle with the angel/man in Genesis 32:22-32, we might explore how the difficulties of representing human and divine male bodies are also bound up with certain scriptings of what these ...
Tongue, Samuel
core  

Sensitivity of synthetic aperture laser optical feedback imaging

open access: yes, 2012
In this paper we compare the sensitivity of two imaging configurations both based on Laser Optical Feedback Imaging (LOFI). The first one is direct imaging, which uses conventional optical focalisation on target and the second one is made by Synthetic ...
Aleksoff   +33 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Transferencias condicionadas y reducción de la pobreza en México: Entre lo real y lo imaginado

open access: yesEuropean Review of Latin American and Caribbean Studies, 2012
: Conditional cash transfers and reduction of poverty in Mexico: Between reality and fantasyIn a longitudinal analysis, this study considers the changes in the well-being of beneficiary households of Mexico's conditional cash transfer (CCT) programme ...
Israel Banegas-González y Minor Mora-Salas   +1 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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