Results 101 to 110 of about 14,995 (285)
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Thanks to ultrasonography, computed tomography, and nuclear magnetic resonance, not only symptomatic but also asymptomatic liver tumors are discovered more frequently than before. Focal nodular hyperplasia (FNH) is one such tumor, most frequently an asymptomatic tumor of the liver, which predominantly appears in women during the generative period, who ...
Čolović Radoje +3 more
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
In order to focus hard X- and gamma-rays it is possible to make use of a Laue lens as a concentrator. With this optical tool it would be possible to improve the detection of radiation for several applications, spanning from the observation of the most ...
Camattari, Riccardo, Guidi, Vincenzo
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
El afán de encontrar un criterio único-formal-universal para la identificación del sujeto -o de cualquier otra categoría gramatical-, como se da el caso en ciertas corrientes teóricas, es una postura que nos hace correr el riesgo o «de acostar las ...
Francesc Queixalós
doaj
The Red Narrator: A Narratological Analysis of Ivan Ivanovic’s Novel Red King
The stratification of the narrative world of the Red King is obvious and the degree of the narrator’s involvement in the story varies with the given narrative situation.
Birsena Džanković
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
MULTIPLE POINT OF VIEW IN THE NOVEL AND FILM "THE HUNT FOR WOLVES"
Ivaylo Petrov is the last great connoisseur of the Bulgarian village among the classics of our literature. In his novel “The Hunt for Wolves,” he depicts the human drama of the transition to collectivization of property in the 1940s and 1950s, which ...
Vladimir Donev
doaj +1 more source

