Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Marketing behind charity: Media narratives of tobacco industry donations in China. [PDF]
Chen Y +9 more
europepmc +1 more source
Utility of BeBack crossing catheter in fistula creation during percutaneous deep vein arterialization. [PDF]
Ong DY, Yong E, Pua U.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Subacute sclerosing panencephalitis in a child six years after measles infection. [PDF]
Le Feur L +6 more
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Holographic Lenses for See-Through Applications Recorded Without Prisms. [PDF]
Sirvent-Verdú JJ +6 more
europepmc +1 more source
Structural Variability Shows Power-Law Based Organization of Vowel Systems. [PDF]
Zhang M, Gong T.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Scalable lens-enhanced broadbeam mmWave harvester delivering tens of milliwatts for wireless power transfer in next-generation smart city environments. [PDF]
Joshi M +3 more
europepmc +1 more source

