Results 51 to 60 of about 1,597 (260)
Annales Universitatis Paedagogicae Cracoviensis. Studia Poetica, 2018 Without the Choice? On the Loss of Axiological Heroes of Children and Youth Literature (on Selected Examples of the Work of Ewa Przybylska and Barbara Kosmowska) Article concerns problems of „new character” which appears in literature of the end of XX ...
Dorota Michułka
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Focal and Non-Focal Epilepsy Localization: A Review
IEEE Access, 2018 The focal and non-focal epilepsy is seen to be a chronic neurological brain disorder, which has affected $\approx ~60$ million people in the world. Hence, an early detection of the focal epileptic seizures can be carried out using the EEG signals, which act as a helpful tool for early diagnosis of epilepsy.
Ahmed Faeq Hussein +7 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Combining Linguistic Methods of Studying Egocentric Units in Russian Translated Narratives
Вестник Кемеровского государственного университета, 2020 The present research featured a functional comparative analysis of egocentric language units in contemporary Russian translated narratives, namely six Russian translations of The Adventures of Tom Sawyer.
A. V. Urzha
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Studia Universitatis Moldaviae: Stiinte Umanistice, 2007 Conceptul de focalizare, ce desemnează perspectiva naratorului sau a personajului în textul narativ, constituie o sursă de investigare relativ controversată, fapt ce îşi găseşte reflectare nu doar în lipsa unui sistem bine definit de termeni (centru ...
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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