Results 181 to 190 of about 6,297,015 (317)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Leni Riefenstahl and Propaganda Film

, 2004
Focus on German Studies
core  

The Effects of Different Attentional Focus During Walking on Prefrontal Cortical Activation in Young Healthy Adults. [PDF]

Eur J Neurosci
Grain T, Ozsancak C, Bonnal J, Auzou P, Prieur F.   +4 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Robust Shape-from-Focus via Physics-Inspired Distortion-Aware Focal Depth Regression. [PDF]

Sensors (Basel)
Li X, Shen W, Li J, Zhai Z, Guan X, Lei Z.   +5 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Young adults' perspectives on chlamydia-related subfertility and a potential predictive subfertility test: A mixed-methods study in the Netherlands. [PDF]

PLoS One
Hoenderboom BM, Alexiou ZW, Peters CMM, Kampman K, van Bokhoven-Rombouts C, Hoebe CJPA, van Benthem BHB.   +6 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Coping in healthcare personnel: certain coping strategies as predictors of anxiety and depression. [PDF]

BJPsych Open
García-Barja P, Talavera-Velasco B, Vázquez-Estévez D, Luceño-Moreno L.   +3 more
europepmc   +1 more source

Focus on Implantation [PDF]

Reproduction, 2004
openaire   +2 more sources