Clinical decision support for potentially sedating drugs in palliative care: a mixed-methods pilot study. [PDF]
Krauss SH +10 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
The Relationship Among Pain, Intrinsic Capacity, and Fear of Movement in Patients with Knee Osteoarthritis: A Moderated Network Analysis. [PDF]
Yan Z, Zhang F, Lu M, Zhang H, Ding H.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The 4 Ss Framework for Designing Age-Friendly Communities of the Future: Focus Group Study. [PDF]
Hunter I, Lockhart C.
europepmc +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Which types of research and knowledge translation are most likely to lead to public health-informed policy responses to unhealthy commodities? A UK-based cross-sectional survey and focus group-based study. [PDF]
Fabbri A, Matthes BK, Smith KE.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Women's Experiences of Recurrent UTIs: A Qualitative Study of Preventive Management and Decision Support Needs. [PDF]
Hayes CV +6 more
europepmc +1 more source

