Results 201 to 210 of about 3,290,780 (252)

Underserved Latinas' Perceptions and Implications Around Breast Cancer Risk Assessment. [PDF]

Cancer Med
Yap JQ, Raygoza JP, Hernandez V, Gonzalez C, Vachon C, Austin JD.   +5 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Health System Community Partnership to Design an Online Resource to Address Perinatal Information Needs for Black Families: Action Research Study. [PDF]

JMIR Pediatr Parent
Taylor YJ, Dahl A, Isreal M, Spinner C, Sammons L, Fesperman D, Washington R, Mehta S, Howell C, Stamp J, Bundy H, Cobb P, Bridges Community Partner Group.   +12 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Differential effects of attentional focus on drop jump performance with implications for primary level coaches. [PDF]

Sci Rep
Zhang J, Liu L, Yang X, Guan L.
europepmc   +1 more source

Defining Transition and Transition Success: Perspectives From Different Stakeholders. [PDF]

J Appl Res Intellect Disabil
Šiška J, Beadle-Brown J, Káňová Š, Havránková T, Černíková M.   +4 more
europepmc   +1 more source

Molecular identification and phylogenetic analysis of marmots in the Xinjiang's Altai Mountains, a newly discovered plague focus of China. [PDF]

Biochem Biophys Rep
Wang Q, Baikeli M, Luo Y, Wang X, Zhang Y, Zhao J, Tuerhong R, Xiaokaiti M, Rehemu A, Wang X, Mou W.   +10 more
europepmc   +1 more source

A qualitative study exploring barriers and motivators influencing home radon testing decisions and behaviors. [PDF]

Sci Rep
Iuliano K, Papas S, Greco KJ, Adachi-Mejia AM, Knutzen K, Sykes C, Dionne AR, Purvis L, Romano ME, Gunn CM, Rees JR.   +10 more
europepmc   +1 more source

Qualitative insights from patient/caregivers, and clinicians on routine use of the EQ-5D-Y-5L in clinical paediatric care-results from a pilot feasibility and acceptability trial. [PDF]

Qual Life Res
Jones R, Holmes K, Devlin N, Dalziel K, Hiscock H.   +4 more
europepmc   +1 more source