Results 91 to 100 of about 2,020,961 (266)

Focus control of wide-angle metalens based on digitally encoded metasurface

open access: yesOpto-Electronic Advances
Based on the principle of super-symmetric lens with quadratic phase gradient transformation, combined with the principle of digital coding of metasurface, we propose a wide-angle coded metalens for focusing control in two-dimensional space. This metalens
Yi Chen   +9 more
doaj   +1 more source

Comparison of Attention Control and Distraction between Students with and without Learning Impairment [PDF]

open access: yesRavānshināsī-i Afrād-i Istis̠nāyī, 2014
Attention deficit is one of the core elements of learning disorder. Aimed at studying attention deficit, this paper compares attention control and distraction in students with and without learning impairments.
Sajad Basharpoor
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Integrated design and control with a focus on control structures

open access: yes, 2012
The common practice is to design chemical processes and their control systems in sequence. However, process design and control share important decisions, and when the process design is fixed there is little room left to improve the control performance. These observations suggest process design and control should be integrated.
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The effects of time and money scarcity on regulatory focus: The mediating role of sense of control

open access: yesActa Psychologica
Regulatory focus involves two motivational systems: the promotion focus, aimed at achieving positive outcomes through proactive behaviors, and the prevention focus, centered on avoiding negative outcomes.
Yifang Wu   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Developmental changes in control focus

open access: yesThe Proceedings of the Annual Convention of the Japanese Psychological Association, 2022
Iori Tani   +4 more
openaire   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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