Results 71 to 80 of about 2,020,961 (266)
Thinking and action: a cognitive perspective on self-regulation during endurance performance
Self-regulation reflects an individual’s efforts to bring behavior and thinking into line with often consciously desired goals. During endurance activity, self-regulation requires an athlete to balance their speed or power output appropriately to achieve
Noel Edward Brick +3 more
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Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Focus on monitoring and control of complex supply systems
The ongoing rapid transformation of our energy supply challenges the operation and stability of electric power grids and other supply networks. This focus issue comprises new ideas and concepts in the monitoring and control of complex networks to address
Robin Delabays +4 more
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Resurgence in focus: Covid-19 dynamics and optimal control frameworks
The resurgence of Covid-19, accompanied by various variants of the virus, highlights the fact that Covid-19 is still present within the population. The study proposed a Covid-19 dynamical model for analyzing the effect of vaccination and the continuous ...
Evans O. Omorogie +4 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Intranasal fentanyl for pain control: current status with a focus on patient considerations
Eric Prommer, Lisa ThompsonDivision of Hematology/Oncology, Mayo Clinic College of Medicine, Mayo Clinic Hospital, Scottsdale, AZ, USAAbstract: Of several newer delivery systems under development and investigation for the administration of opioids, the ...
Eric Prommer, Lisa Thompson
doaj
BACKGROUND AND OBJECTIVE: Chronic ankle instability is a common injury in athletes that leads to postural control disorders. The aim of this study was to compare the effect of external focus of attention and postural task alone on center of pressure sway
Gh Abolghasemi +4 more
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