Results 101 to 110 of about 7,142,971 (300)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Eigenspace design techniques for active flutter suppression [PDF]

, 1984
The application of eigenspace design techniques to an active flutter suppression system for the DAST ARW-2 research drone is examined. Eigenspace design techniques allow the control system designer to determine feedback gains which place controllable ...
Garrard, W. L., Liebst, B. S.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Focus on monitoring and control of complex supply systems

Journal of Physics: Complexity
The ongoing rapid transformation of our energy supply challenges the operation and stability of electric power grids and other supply networks. This focus issue comprises new ideas and concepts in the monitoring and control of complex networks to address
Robin Delabays, Laurent Pagnier, Benjamin Schäfer, Melvyn Tyloo, Dirk Witthaut   +4 more
doaj   +1 more source

Resurgence in focus: Covid-19 dynamics and optimal control frameworks

Global Epidemiology
The resurgence of Covid-19, accompanied by various variants of the virus, highlights the fact that Covid-19 is still present within the population. The study proposed a Covid-19 dynamical model for analyzing the effect of vaccination and the continuous ...
Evans O. Omorogie, Kolade M. Owolabi, Bola T. Olabode, Tunde T. Yusuf, Edson Pindza   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Comparison of the Effect of External Focus on Postural Control in Athletes with or without Chronic Ankle Instability while Standing on an Unstable Surface

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020
BACKGROUND AND OBJECTIVE: Chronic ankle instability is a common injury in athletes that leads to postural control disorders. The aim of this study was to compare the effect of external focus of attention and postural task alone on center of pressure sway
Gh Abolghasemi, SM Sohani, E Ebrahimi-Takamjani, R Salehi, Sh Asgari   +4 more
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Intranasal fentanyl for pain control: current status with a focus on patient considerations

Patient Preference and Adherence, 2011
Eric Prommer, Lisa ThompsonDivision of Hematology/Oncology, Mayo Clinic College of Medicine, Mayo Clinic Hospital, Scottsdale, AZ, USAAbstract: Of several newer delivery systems under development and investigation for the administration of opioids, the ...
Eric Prommer, Lisa Thompson
doaj