Results 171 to 180 of about 2,199,799 (303)

AI assisted triage of UK patients in mental health care services: a qualitative focus group study of patients' attitudes. [PDF]

BMC Psychiatry
Smith KA, Hamer-Hunt J, Kormilitzin A, Page H, Joyce DW, Cipriani A, CHRONOSIG group*.   +6 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Healthcare quality in rural Armenia: Focus group perceptions : Healthcare quality in rural Armenia. [PDF]

BMC Health Serv Res
Manukyan C, Antonyan L, Hovhannisyan M, Terzan L, Libaridian L.   +4 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Nurses' Perceptions of Fundamental Care in Preventing Venous Ulcer Recurrence: A Qualitative Focus Group Study. [PDF]

Int Wound J
Gomes FJP, Baixinho CL, Monteiro AIC, da Costa AS, Henriques MAP.   +4 more
europepmc   +1 more source

Loking foward, loking back: A quantitative anaysis of a focus group of HIV positive latinas

, 2001
Edna Acosta‐Pérez, Nilda Peragallo
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Professional Adaptation of Foreign Nurses Working in Iceland: A Focus Group Study Guided by the Cross-Cultural Adjustment Model. [PDF]

Nurs Open
Viejo WG, Bragadóttir H, Klinke ME.
europepmc   +1 more source

Themes, groups, and codes identified in the teachers, coaches, managers, and experts focus groups.

Adrián Mateo-Orcajada (21262899), Lucía Abenza-Cano (10528304), Pedro Ángel López-Miñarro (21262902), Lourdes Meroño (9899330), Ana María Gallardo-Guerrero (21262905), María de la Trinidad Morales-Belando (21262908), Noelia González-Gálvez (6646007), Alejandro Espeso-García (9181730), Tomás Abelleira-Lamela (21262911), Nerea Gómez-Cuesta (21262914), Antonio Joaquín García-Velez (21262917), Mario Albaladejo-Saura (18805750), Francisco Esparza-Ros (18249037), Raquel Vaquero-Cristóbal (9899324)   +13 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source