Results 181 to 190 of about 8,007,890 (351)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Conducting successful focus groups and analysis: experience from a pilot study on family planning and sexual behaviour in the era of HIV / AIDS and STDs. [PDF]

, 1998
Stella Neema
openalex  

Mali Focus Group Discussions Data

, 2016
M.R. Bellon, N'Danikou, S., Vodouhe, R., Ntandou-Bouzitou, N.D., Sidibe, A.   +4 more
openalex   +1 more source

FOCUS-GROUP AND ITS IMPACT IN THE QUESTIONNAIRE OF MARKETING RESEARCH ON THE ROMANIAN CAR MARKET [PDF]

Designing a questionnaire is the most profound activity which makes an impact on a research in marketing. The investigation instrument finally determines the quality of this type of research.
CRUCERU Gheorghe, MANEA Constantin, SAVOIU Gheorghe   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Exploring Professionals' Perceptions of the Potential of Digital Twins in Homecare-A Focus Group Study in Sweden. [PDF]

Healthcare (Basel)
Saade S, Nordin S, Borg J.
europepmc   +1 more source

Managing HIV/AIDS in small and medium enterprises (SMEs), with the focus on South Africa : an experience by the International Finance Corporation (IFC), the private sector division of the World Bank Group

, 2007
Laetitia Enslin
openalex   +1 more source

Explorations in feminist participant-led research: Conducting focus group discussion with polyamorous women

, 2005
This paper addresses the methodology used in research centring on a group of polyamorous women. It outlines the methodological processes of participant led research and highlights some key ethical and epistemological considerations.
Barker, Meg, Ritchie, Ani
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Predicting entrepreneur fundraising success from focus group EEG data. [PDF]

PLoS One
Yun JH, Heaton S, Wong JS, Klein P, Platt ML.   +4 more
europepmc   +1 more source