Results 171 to 180 of about 2,268,232 (304)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Use of Focus Groups to Identify Concerns About Dialysis

open access: yes, 1999
Sadler, John H.   +8 more
core   +1 more source

Traceability: European consumers' perceptions regarding its definition, expectations and differences by product types and importance of label schemes

open access: yes
Given the heterogeneity of European consumers it is not unsurprising that they have different perceptions and expectations regarding (but also understanding thereof) 'traceability'.
Chrysochou, Polymeros E.   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

COMBINING TASTE PANELS WITH FOCUS GROUPS TO ELICIT CONSUMER PREFERENCES TOWARD A NEW SHRIMP PRODUCT

open access: yes
Consumer/Household Economics,
Otwell, W. Steven   +3 more
core  

Challenges of Joint Crisis Plans with Migrant Patients: Focus Groups with Mental Health Professionals and Interpreters. [PDF]

open access: yesCommunity Ment Health J
Weber O   +7 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Understanding overdose risk and response in permanent supportive housing: results of focus groups with tenants, staff, and leaders. [PDF]

open access: yesAddict Sci Clin Pract
Gaeta Gazzola M   +9 more
europepmc   +1 more source

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