Results 131 to 140 of about 11,077,430 (333)

Development of Lifelong learning through libraries- use of the web pages as a marketing channel in University Libraries of Sri Lanka [PDF]

, 2007
Lifelong learning is a concept that a person engages in learning process throughout the whole his/her lifetime by using acquired knowledge and skills, by experiencing in different circumstances, and critical thinking.
Garusing Arachchige, J. J.
core  

The RD53 Collaboration's SystemVerilog-UVM Simulation Framework and its General Applicability to Design of Advanced Pixel Readout Chips

, 2014
The foreseen Phase 2 pixel upgrades at the LHC have very challenging requirements for the design of hybrid pixel readout chips. A versatile pixel simulation platform is as an essential development tool for the design, verification and optimization of ...
Christiansen, J., Conti, E., Hemperek, T., Marconi, S., Placidi, P.   +4 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Out From Behind the Firewall: Towards Better Library IT Communications

Code4Lib Journal, 2013
Traditionally, IT departments lack a strong focus on communications and promotions. Numerous exciting projects and services are created by library IT departments and web development teams daily, but resources for promotion are typically unavailable or ...
Lisa Gayhart
doaj  

Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library. [PDF]

Eur J Med Chem, 2020
Gibbons GS, Chakraborty A, Grigsby SM, Umeano AC, Liao C, Moukha-Chafiq O, Pathak V, Mathew B, Lee YT, Dou Y, Schürer SC, Reynolds RC, Snowden TS, Nikolovska-Coleska Z.   +13 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis. [PDF]

ACS Med Chem Lett, 2020
Luo D, Luesch H.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Lunar e-Library: A Research Tool Focused on the Lunar Environment [PDF]

As NASA plans and implements the Vision for Space Exploration, managers, engineers, and scientists need lunar environment information that is readily available and easily accessed.
Ferguson, Dale, Finckenor, Miria, McMahan, Tracy A., Shea, Charlotte A.   +3 more
core   +1 more source