Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
High-throughput sheathless focusing and sorting of flexible microalgae in spiral-coupled contraction-expansion channels. [PDF]
Zhou T +7 more
europepmc +1 more source
The effect of cognitive appraisal and problem-focused coping on smoking treatment outcome
Charles C. Lampton
openalex +1 more source
INTERCEPT (INTERnational mediCal graduatE comPrehensive inducTion) programme Evaluation study - Evaluating a bespoke comprehensive induction with a focus on integration of International Medical Graduates Beginning Work in the UK v1 [PDF]
Dr Roshelle Ramkisson +12 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A Novel Compact Multi-Reflecting Time-of-Flight Mass Spectrometer. [PDF]
Verenchikov AN +9 more
europepmc +1 more source
After great pain: a journey to understanding pain and nerve compression syndromes, with a focus on athletes [PDF]
Elisabet Hagert, Catherine Curtin
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
How do nature-based interventions increase the resilience of older persons? A best fit framework synthesis. [PDF]
Cornu T +5 more
europepmc +1 more source

