Results 251 to 260 of about 13,955,013 (337)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Intensity-asymmetric wavefront shaping in nonlocal meta-lens. [PDF]

Nat Commun
Yao J, Wang Z, Fan Y, Zhang K, Lin R, Wu J, Peng C, Xiao S, Tsai DP.   +8 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Equity, Diversity, Inclusion and Accessibility in pharmacy education: a scoping review protocol. [PDF]

BMJ Open
Kan I, Vander Kloet MA, Lein RK, Koehler T, Blokzijl MR, Mantel-Teeuwisse AK, Alfarah M.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Theoretical Study of High-Order Velocity Focusing Achieved with Single-Stage Reflectron Time-of-Flight Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom
Cai YH, Wang YS.
europepmc   +1 more source

Fabrication of Terahertz Fresnel Zone Plates via Ultraprecision Mechanical Processing. [PDF]

Micromachines (Basel)
Chen M, Wang J, Fang F.
europepmc   +1 more source

Development of the First Patient-Reported Experience Measure (PREM) for Hearing Loss in Audiology Care-My Hearing PREM. [PDF]

Health Expect
English K.
europepmc   +1 more source

Machine learning-driven single-cell phenotyping in size-controlled microenvironments <i>via</i> parallel deterministic droplet microfluidics.

Lab Chip
Lee S, O'Donnell S, Peng Z, Shin JW.
europepmc   +1 more source

Ultra-coherent meta-emitter tailors arbitrary thermal wavefront. [PDF]

Nat Commun
Chen R, Chen T, Liu M, Liu X, Zhang S, Raza F, Dong H, Dang Y, Yu Z, Hu H, Xu J, Qiu CW, Ma Y.   +12 more
europepmc   +1 more source