Results 21 to 30 of about 39,406 (219)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Ectopia Cordis with Omphalocele in First Trimester Pregnancy: A Case Report of Incomplete Type of Pentalogy of Cantrell [PDF]

International Journal of Anatomy Radiology and Surgery
Ectopia Cordis (EC) is a rare congenital malformation in which the heart is located partially or totally outside the thoracic cavity. It results from the failure of migration of the lateral mesoderm into the midline.
Arumulla Mithilesh, Hira Muhammed, Yugandhar Samireddypalle, Nanditha Jangamreddy   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Foetal Autopsy: A Cross-sectional Study of 41 Cases at a Tertiary Care Centre in Kuppam, Andhra Pradesh, India [PDF]

National Journal of Laboratory Medicine
Introduction: Perinatal mortality includes both late foetal deaths and early neonatal deaths. The perinatal mortality rate in India was 23/1000 live births for the year 2016, with congenital anomalies being the major cause of perinatal mortality.
Reshma Anegundi, Vaddavalli Vidhya Dhari, CA Arathi   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Litter-size-dependent intrauterine growth restriction in sheep

Animal, 2007
Regulation of foetal development in sheep depends on interactions between the intrinsic capacity of the foetus for growth and the maternal environment.
E. Gootwine, T.E. Spencer, F.W. Bazer
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Używki w ciąży – alcohol = Stimulants in pregnancy – alcohol

Journal of Education, Health and Sport, 2015
Pawłowska-Muc Agnieszka Konstancja, Łepecka-Klusek Celina, Pilewska-Kozak Anna Bogusława, Stadnicka Grażyna. Używki w ciąży – alcohol = Stimulants in pregnancy – alcohol. Journal of Education, Health and Sport. 2015;5(8):385-394. ISSN 2391-8306.
AGNIESZKA KONSTANCJA PAWŁOWSKA-MUC, CELINA ŁEPECKA-KLUSEK, ANNA PILEWSKA-KOZAK, GRAŻYNA STADNICKA   +3 more
doaj  

Luna Virus and Helminths in Wild Mastomys natalensis in Two Contrasting Habitats in Zambia: Risk Factors and Evidence of Virus Dissemination in Semen

Pathogens, 2022
Transmission dynamics and the maintenance of mammarenaviruses in nature are poorly understood. Using metagenomic next-generation sequencing (mNGS) and RT-PCR, we investigated the presence of mammarenaviruses and co-infecting helminths in various tissues ...
Samuel Munalula Munjita, Given Moonga, Andrew Nalishuwa Mukubesa, Joseph Ndebe, Benjamin Mubemba, Manu Vanaerschot, Cristina Tato, John Tembo, Nathan Kapata, Simbarashe Chitanga, Katendi Changula, Mashiro Kajihara, Walter Muleya, Ayato Takada, Elisabeth Fichet-Calvet, Alimuddin Zumla, Hirofumi Sawa, Matthew Bates, Sody Munsaka, Edgar Simulundu   +19 more
doaj   +1 more source