Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Teratogenic Test of Pandanus Conoideus Var. Yellow Fruit Extract to Development of Rat Embryo (Rattus Norvegicus) [PDF]
Muna L, Astirin OP, Sugiyarto. 2010. Teratogenic test of Pandanus conoideus var. yellow fruit extract to development of ratembryo (Rattus norvegicus). Nusantara Bioscience 2: 126-134.
ASTIRIN, O. P. (OKID) +2 more
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Ectopia Cordis with Omphalocele in First Trimester Pregnancy: A Case Report of Incomplete Type of Pentalogy of Cantrell [PDF]
Ectopia Cordis (EC) is a rare congenital malformation in which the heart is located partially or totally outside the thoracic cavity. It results from the failure of migration of the lateral mesoderm into the midline.
Arumulla Mithilesh +3 more
doaj +1 more source
The Foetus, His Humanity and His Rights [PDF]
Dr. De Marco is a frequent contributor to Linacre. His current article examines the relationship of the word human and the mode of application of that term to the ...
De Marco, Donald
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Foetal Autopsy: A Cross-sectional Study of 41 Cases at a Tertiary Care Centre in Kuppam, Andhra Pradesh, India [PDF]
Introduction: Perinatal mortality includes both late foetal deaths and early neonatal deaths. The perinatal mortality rate in India was 23/1000 live births for the year 2016, with congenital anomalies being the major cause of perinatal mortality.
Reshma Anegundi +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Litter-size-dependent intrauterine growth restriction in sheep
Regulation of foetal development in sheep depends on interactions between the intrinsic capacity of the foetus for growth and the maternal environment.
E. Gootwine, T.E. Spencer, F.W. Bazer
doaj +1 more source
Foetus acardius amorphus [PDF]
Summary A case of acardius amorphus is reported. The rarity of foetal monsters without a functioning heart is emphasized and the method of classification reviewed. The theories of teratogenesis are discussed. Evidence is presented in support of the theory that there is a primary failure of the organ to develop.
openaire +2 more sources

