Results 271 to 280 of about 80,893 (323)

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

Advanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su, Qi Qi, Yi Fan, Yubo Wang, Gaoyang Hao, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +7 more
wiley   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

Advanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong, Haijun Huang, Yuxiu Wang, Bo Jiang, Yuzheng Chen, Huanhuan Xu, Jing Ren, Shengnan Guo, Tianhao Li, Mingjie Zhang, Tianyu Zhai, Wenbo Yang, Kaidong Liu, Cheng Lyu, Jingxuan Kang, Mingshuo Zhang, Yupeng Lu, Binghui Si, Shujun Cao, Dandan Xu, Zong Chen, Dapeng Hao   +21 more
wiley   +1 more source

Ultrafast Interfacial Engineering for Quantifiable Control of Asymmetric Configurations in Nanostructured Janus Membranes

Advanced Science, EarlyView.
Founded on a rapidly formed nanostructured tannic acid/polyethyleneimine (TA/PEI) platform, an ultrafast (∼5 min), universal interfacial engineering strategy utilizing stearoyl chloride (SC) and Phytic acid (PA) enables precise fabrication of Janus membranes across diverse substrates.
Wenqing Zhang, Jinhui Xu, Bo Li, Yao Li, Yue Zhang, Zhishu Tang, Huaxu Zhu, Jingwei Hou   +7 more
wiley   +1 more source

Optimizing multi-objective task scheduling in fog computing with GA-PSO algorithm for big data application. [PDF]

Front Big Data
Saad M, Enam RN, Qureshi R.
europepmc   +1 more source

Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle

Advanced Science, EarlyView.
Using fiber photometry and genetically encoded sensors, the dynamic release patterns of four neuromodulators in the olfactory tubercle (OT)—a brain region overlapping with the olfactory cortex and ventral striatum—were systematically monitored in response to external rewards and distinct reward‐associated learning processes.
Maojun Hong, Liuting Zou, Yiqing Chen, Juan Guo, Zhixiang Xu, Tong Ma, Shuaishuai Hu, Rongfeng K. Hu   +7 more
wiley   +1 more source

Injectable Porous Microspheres Loaded With Biomimetic Preconditioned Bone Marrow Mesenchymal Stem Cell‐Derived Exosomes for Vascularized Bone Regeneration

Advanced Science, EarlyView.
Schematic illustration of injectable PDA‐modified GelMA microspheres loaded with BioPre‐Exos for vascularized bone regeneration. ABSTRACT Critical‐sized bone defects remain a highly challenging clinical problem due to insufficient intrinsic self‐healing capacity.
Lijun Li, Hao Zhang, Lingtong Sun, Yingfeng Su, Yang Xu, Jian Huang, Jingchao Wen, Jinjin Zhu, Jianjun Ma, Wenbin Xu   +9 more
wiley   +1 more source

DengueFog: A Fog Computing-Enabled Weighted Random Forest-Based Smart Health Monitoring System for Automatic Dengue Prediction. [PDF]

Diagnostics (Basel)
Kukkar A, Kumar Y, Sandhu JK, Kaur M, Walia TS, Amoon M.   +5 more
europepmc   +1 more source

Maintaining Security of Patient Data by Employing Private Blockchain and Fog Computing Technologies based on Internet of Medical Things

Mishall Al-Zubaidie, Rasha Halim Razzaq
openalex   +2 more sources

Optimizing Internet of Things Fog Computing: Through Lyapunov-Based Long Short-Term Memory Particle Swarm Optimization Algorithm for Energy Consumption Optimization. [PDF]

Sensors (Basel)
Pan S, Huang C, Fan J, Shi Z, Tong J, Wang H.   +5 more
europepmc   +1 more source

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Fog Computing

IEEE Internet Computing, 2017
Fog computing could alleviate many of the Internet of Things' unique challenges. This special issue explores fog computing's opportunities and challenges to form a distributed and virtualized platform, supporting computation-intensive tasks and distributing advanced computing, storage, networking, and management services to the edge of the network ...
Marcus Oppitz, Peter Tomsu
  +5 more sources