Results 101 to 110 of about 74,449 (307)

Fortification and health: challenges and opportunities. [PDF]

, 2015
Fortification is the process of adding nutrients or non-nutrient bioactive components to edible products (e.g., food, food constituents, or supplements). Fortification can be used to correct or prevent widespread nutrient intake shortfalls and associated
Bailey, Regan L, Dary, Omar, Dwyer, Johanna T, Gaine, P Courtney, Jarvis, Ashley B, Keen, Carl L, King, Janet C, Miller, Kevin B, Philbert, Martin A, Tarasuk, Valerie, Taylor, Christine L, Wiemer, Kathryn L   +11 more
core  

An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry [PDF]

, 2010
Background: The goal of this study was to develop and to validate an improved isotope-dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of methylmalonic acid (MMA) in urine.
Bolann BJ, Klee GG, Kushnir MM, Magera M, Rasmussen K   +4 more
core   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation

BMC Biology
Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder affecting one-third of the global population, encompasses a spectrum ranging from fatty liver to severe hepatic steatosis.
Wan-Yu Chi, Gang-Hui Lee, Ming-Jer Tang, Bing-Hung Chen, Wei-Ling Lin, Tzu-Fun Fu   +5 more
doaj   +1 more source

Serum folate and dietary folate intake in beta thalassaemia trait: a case–control study from Sri Lanka

BMJ Open
Objectives Ineffective erythropoiesis, although at a mild degree, could make individuals with beta thalassaemia trait (BTT) vulnerable to folate deficiency.
Anuja Premawardhena, Shyamali Thilakarathne, Udayanga Prasad Jayaweera, Thushari Uthpala Herath, Renuka Silva   +4 more
doaj   +1 more source

Folate deficiency affects histone methylation

Medical Hypotheses, 2016
Formaldehyde is extremely toxic reacting with proteins to crosslinks peptide chains. Formaldehyde is a metabolic product in many enzymatic reactions and the question of how these enzymes are protected from the formaldehyde that is generated has largely remained unanswered.
Garcia, Benjamin A., Luka, Zigmund, Loukachevitch, Lioudmila V., Bhanu, Natarajan V., Wagner, Conrad   +4 more
openaire   +2 more sources

Severe experimental folate deficiency in a human subject - a longitudinal investigation of red-cell folate immunoassay errors as megaloblastic anaemia develops [PDF]

, 2014
BACKGROUND: The few published studies comparing results between commercial red-cell folate immunoassays have found significant differences. None have provided longitudinal data during the development of megaloblastic anaemia from severe folate deficiency.
Paul Golding
core   +1 more source

Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial

BMC Psychiatry, 2007
Background Clinical depression is common, debilitating and treatable; one in four people experience it during their lives. The majority of sufferers are treated in primary care and only half respond well to active treatment. Evidence suggests that folate
Whitaker Rhiannon, Tranter Richard, Slegg Gary, Pirmohamed Munir, Moat Stuart, Hughes Dyfrig, Lloyd Keith, Bedson Emma, Roberts Seren, Wilkinson Clare, Russell Ian   +10 more
doaj   +1 more source

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

Animal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem, Samy A. Elsaadawy, Zhaohai Wu, Lu Ma, Todd R. Callaway, Dengpan Bu   +5 more
wiley   +1 more source

Clinical utility of serum folate measurement in tertiary care patients: Argument for revising reference range for serum folate from 3.0 ng/mL to 13.0 ng/mL

Practical Laboratory Medicine, 2015
Objective: Assess the need for folate testing, frequency of corrective action, and determine reference level for serum folate. Methods: Serum folate levels in 5313 samples from 4448 patients, and clinical data were reviewed for patient characteristics ...
Gurmukh Singh, Hana Hamdan, Vivek Singh
doaj   +1 more source