Results 51 to 60 of about 74,449 (307)

Effect of folate status and methylenetetrahydrofolate reductase genotypes on the complications and outcome of high dose methotrexate chemotherapy in north Indian children with acute lymphoblastic leukemia

Indian Journal of Medical and Paediatric Oncology, 2016
Purpose: The genes of the folate metabolic pathway have been associated with toxicities during high dose methotrexate therapy for childhood ALL, however, the importance of intrinsic folate status in this regard is unclear.
Nirmalya Roy Moulik, Archana Kumar, Suraksha Agrawal, Abbas Ali Mahdi, Ashutosh Kumar   +4 more
doaj   +1 more source

Vitamin B12 deficiency--a major cause of megaloblastic anaemia in patients attending a tertiary care hospital [PDF]

, 2009
BACKGROUND: Folate and vitamin B12 deficiencies have been known to cause megaloblastic anaemia. Since the deficiencies of these two vitamins are very common in Pakistani population, it would be imperative to investigate their role in causing ...
Iqbal, Saira Perwaiz, Iqbal, Saleem Perwaiz, Kakepoto, Ghulam Nabi   +2 more
core   +1 more source

Maternal serum zinc deficiency in cases of neural tube defect in Gorgan, north Islamic Republic of Iran [PDF]

, 2009
Previous studies have shown a high rate of neural tube defects (NTD) in Gorgan, northern Islamic Republic of Iran. This case-control study during 2003-04 compared serum zinc levels and other variables in 23 mothers of neonates affected with NTD and 36 ...
Golalipour, M.J., Mansourian, A.R., Mobasheri, E., Vakili, M.A.   +3 more
core   +1 more source

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes [PDF]

, 2018
Growing evidence shows that improper intake of vitamin B6 increases cancer risk and several studies indicate that diabetic patients have a higher risk of developing tumors.
MF Fenech, M Fenech, F Mitelman, A Aguilera, SF Bunting, SJ Duthie, MJ Shrubsole, YI Kim, JB Mason, CD Cantarella, R Percudani, R Percudani, ML Salvo di, H Hellmann, AA Booth, P Bilski, SA Denslow, BN Ames, L Galluzzi, S Mocellin, L Galluzzi, B Gylling, A Marzio, P Kanellis, SC Lee, M Brownlee, D Bonnefont-Rousselot, Y Hinokio, MT Goodarzi, E Tatsch, P Graham, RS Garofalo, RW Alfa, LP Musselman, SN Thompson, R Ugrankar, R Bohni, M Tatar, JM Murillo-Maldonado, M Lorenzi, A Rezabakhsh, SE Polo, JP Madigan, PA Jeggo, C Merigliano, H Vlassara, H Stopper, N Schupp, S Golbidi, EA Muellenbach, J Colombani, AT Haselton, SK Kim, G Lee, EJ Rulifson, SJ Broughton, T Ikeya, M Fraser, S Nakamura, M Pischetsrieder, S Nakamura, J Blasiak, PT Clayton, M Okada, JE Leklem, HJ Ahn, WA Nix, M Gatti, S Bonaccorsi, FJ Diaz-Benjumea   +69 more
core   +2 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy [PDF]

, 2016
Background: The uremic milieu exposes chronic kidney disease (CKD) patients to premature ageing processes. The impact of renal replacement therapy (dialysis and renal transplantation [RTx]) or immunosuppressive treatment regimens on ageing biomarkers has
Bárány, Peter, Curley, Hannah, Genberg, Helena, Luttropp, Karin, McGuinness, Dagmara, Nordfors, Louise, Quasim, Tara, Qureshi, Abdul Rashid, Sandberg, John, Schalling, Martin, Shiels, Paul G., Stenvinkel, Peter, Sönnerborg, Isabella, Wennberg, Lars   +13 more
core   +1 more source

Rethinking Extracellular Vesicle Signaling

Advanced Materials, EarlyView.
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley   +1 more source

Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal

Journal of Nutritional Science, 2021
The demand for cobalamin (vitamin B12) and folate is increased during pregnancy, and deficiency during pregnancy may lead to complications and adverse outcomes. Yet, the status of these micronutrients is unknown in many populations.
Catherine Schwinger, Shakun Sharma, Ram K. Chandyo, Mari Hysing, Ingrid Kvestad, Manjeswori Ulak, Suman Ranjitkar, Merina Shrestha, Laxman P. Shrestha, Adrian McCann, Per M. Ueland, Tor A. Strand   +11 more
doaj   +1 more source