Results 171 to 180 of about 222,091 (247)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Backbone double-mutant cycle analysis quantifies hydrogen-bond energies in proteins. [PDF]

Protein Sci
Zheng H, Newberry RW.
europepmc   +1 more source

Some considerations about fold models

The Journal of the Geological Society of Japan, 1973
openaire   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

A subject-specific reversible folding model reveals geometry-driven white-matter organization

Osman B, Vink R, Jalba AC, Schilling KG, Chamberland M.   +4 more
europepmc   +1 more source

Limitations of the refolding pipeline for de novo protein design. [PDF]

Protein Sci
Korbeld KT, Viliuga V, Fürst MJLJ.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Benchmarking antigen-aware inverse folding methods for antibody design. [PDF]

Bioinform Adv
Janusz B, Chomicz D, Wrobel S, Dudzic P, Polasa A, Martin K, Darnell S, Comeau SR, Krawczyk K.   +8 more
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Sequence-Encoded Frustration Directs the Formation of Abridged G-Quadruplex Architectures. [PDF]

Angew Chem Int Ed Engl
Qian Y, Ali MY, Karsisiotis AI, Dillon P, Dvorkin SA, McPherson PAC, Webba da Silva M.   +6 more
europepmc   +1 more source