Results 151 to 160 of about 10,115,388 (315)
Right Lung Model featuring Upper, Middle and Lower Lobes [PDF]
, 2020 This is a multi-colored right lung model where each color designates a segment of the upper, middle, and lower lobes.
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Reverse modeling and simulation for folding and deployment of inflatable aerodynamic decelerator
Hangkong gongcheng jinzhanThe folding and development performance and aerodynamic bearing capacity of the inflatable aerodynamic decelerator are two key issues in its safety evaluation.
LEI Qing +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
UMYU Scientifica JournalThe analysis of the deuteron scattering from was performed in the elastic channel using the double-folding model to evaluate the optical potentials of the present study.
Raymond C Abenga +2 more
doaj +1 more source
A Self-Assisting Protein Folding Model for Teaching Structural Molecular Biology. [PDF]
Structure, 2017 Davenport J +5 more
europepmc +1 more source
Benchmarking inverse folding models for antibody CDR sequence design
PLOS OneAntibody-based therapies are at the forefront of modern medicine, addressing diverse challenges across oncology, autoimmune diseases, infectious diseases, and beyond. The ability to design antibodies with enhanced functionality and specificity is critical for advancing next-generation therapeutics.
Li, Y +5 more
openaire +4 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
$\Omega$-deuteron Interaction in Folding Model
, 2019 A simple single folding model for $\Omega$-deuteron with maximal spin $\left(I\right)J^{P}=\left(0\right)5/2^{+}$ is investigated. $\Omega$ is assumed to orbit an unperturbed deuteron in a $\Omega$-deuteron potential based on a separable $\Omega$-nucleon potential from lattice QCD.
Etminan, Faisal +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source