Results 51 to 60 of about 16,055 (293)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
On some infinitesimal automorphisms of Riemannian foliation
In Riemannian foliation, a transverse affine vector field preserves the curvature and its covariant derivatives. In this paper we solve the converse problem.
Ali Chaouch, Mohamed +1 more
core +1 more source
Characterization of second type plane foliations using Newton polygons
In this article we characterize the foliations that have the same Newton polygon that their union of formal separatrices, they are the foliations called of the second type.
Fernández-Sánchez Percy +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ultrasonic image logs acquired in the DFDP‐2B borehole yield the first continuous, subsurface description of the transition from schist to mylonite in the hangingwall of the Alpine Fault, New Zealand, to a depth of 818 m below surface. Three feature sets
Cécile Massiot +12 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Geometric properties of the Minkowski operator
This article is about Minkowski difference of sets, which is one of the Minkowski operators. The necessary and sufficient conditions for the existence of the Minkowski difference of given regular polygons in the plane were derived. The method of finding
M.Sh. Mamatov +3 more
doaj +1 more source
On holomorphic one-forms transverse to closed hypersurfaces
In this note we announce some achievements in the study of holomorphic distributions admitting transverse closed real hypersurfaces. We consider a domain with smooth boundary in the complex affine space of dimension two or greater. Assume that the domain
Toshikazu Ito, Bruno Scárdua
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Holonomy pseudogroups as obstructions to equivalence of manifolds over the algebra of dual numbers
A smooth manifold over the algebra of dual numbers D (a D-smooth manifold) carries the canonical foliation whose leaves are affine manifolds. Extension of charts on a D-smooth manifold along leaf paths allows ones to associate with an immersed ...
A.A. Malyugina, V.V. Shurygin
doaj +1 more source

